Symptom/severity measure | Initial visit (n=16) | Final visit (n=15#) |
Clinical | ||
FEV1 % predicted mean±sd | 89±19 | 69**±22 |
Elevated C-reactive protein | 4 (25%) | 11* (73%) |
Cough | 13 (81%) | 15 (100%) |
Haemoptysis | 5 (31%) | 2 (13%) |
Fever | 1 (6%) | 3 (20%) |
Night sweats | 3 (19%) | 5 (33%) |
Fatigue | 4 (25%) | 3 (20%) |
Sputum | 13 (81%) | 13 (87%) |
Shortness of breath | 6 (38%) | 5 (33%) |
Weight loss | 2 (13%) | 3 (20%) |
Radiographic | ||
Cavitary | 1 (6%) | 7* (47%) |
Reiff score ≥3 lobes or 1 lobe with cystic BE | 12 (75%) | 13 (87%) |
Microbiological | ||
Smear quantity* | ||
Negative | 7 (44%) | 4 (25%) |
Few | 2 (13%) | 1 (6%) |
Moderate | 5 (31%) | 1 (6%) |
Many | 2 (13%) | 9 (56%) |
Culture quantity¶ median (IQR) | 3 (3–6) | 5 (3–6) |
FEV1: forced expiratory volume in 1 s; BE: bronchiectasis; IQR: interquartile range. #: no clinical or radiographic data were available within 365 days of the final visit for one patient, so for these variables, n=15; ¶: according to a semiquantitative scale of 1 (liquid media only), 2 (one colony), 3 (scant), 4 (light), 5 (moderate) and 6 (heavy). *: p<0.05; **: p<0.01.