TABLE 6

Adjusted mean change in lung function over the previous 20 years by snoring or nocturnal gastro-oesophageal reflux (nGOR) at follow-up

No snoringWith snoringp-valueNo nGORWith nGORp-value
Multiple linear regression, change between ECRHS I and III (∼20 years)
 Change in pre-bronchodilator  FEV1 % pred−4.55 (−5.85– −3.25)−5.33 (−6.63– −4.03)0.11−4.65 (−5.95–3.35)−5.30 (−6.43– −4.16)0.35
 Change in pre-bronchodilator  FVC % pred−0.79 (−1.89–0.32)−1.28 (−2.60–0.05)0.16−0.87 (−1.98–0.24)−1.10 (−2.65–0.46)0.72
Multiple linear regression, change between ECRHS II and III (∼10 years)
 Change in pre-bronchodilator  FEV1 % pred−4.58 (−5.65– −3.52)−5.53 (−6.53– −4.53)0.04*−4.70 (−5.71– −3.68)−5.31 (−6.52– −4.09)0.23
 Change in pre-bronchodilator  FVC % pred−0.99 (−2.07–0.99)−1.94 (−2.81– −1.07)0.03*−1.10 (−2.10– −0.10)−1.47 (−2.82– −0.13)0.51

Data in parentheses are 96% confidence intervals. Adjusted for baseline body mass index (BMI), BMI change, pack-years before study, pack-years over study time, baseline lung function value, study time and centre. ECRHS: European Community Respiratory Health Survey; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity. *: p<0.05.