Cut-off | Test | Sensitivity | Specificity | PPV | NPV |
10% | TST | 80% | 48% | 47% | 81% |
QFT | 85% | 40% | 23% | 93% | |
ESAT-6 | 100% | 36% | 19% | 100% | |
CFP-10 | 100% | 35% | 17% | 100% | |
All | 88% | 39% | 25% | 94% | |
50% | TST | 54% | 71% | 58% | 67% |
QFT | 50% | 69% | 26% | 87% | |
ESAT-6 | 69% | 66% | 23% | 94% | |
CFP-10 | 60% | 65% | 18% | 92% | |
All | 57% | 67% | 31% | 86% |
Results for TST and interferon-γ release assays are presented separately and in combination, i.e. positive result and/or conversion in any test, as well as negative result in all tests. QFT: QuantiFERON TB Gold In-Tube; ESAT-6: 6-kDa early secretory antigenic target; CFP-10: 10-kDa culture filtrate protein.