Nearby gene | Function/location | SNV | Unconditioned p-value | Conditioned p-value |
MUC5AC | Missense (Ala5353Lys) | rs34474233# | 2.99×10−9 | 4.12×10−3 |
MUC5AC | Missense (Ala5353Lys) | rs34815853# | 4.15×10−9 | 6.27×10−3 |
MUC5B | 8.1 kb 5′ of MUC5B | rs12802931 | 3.72×10−16 | 0.731 |
MUC5B/RP11-532E4.2 | Missense/intronic | rs200243273 | 3.55×10−8 | 1.44×10−4 |
CTD-2245O6.1 | 31 kb 3′ of CTD-2245O6.1 | rs4963073 | 4.91×10−8 | 1.48×10−6 |
CTD-2245O6.1 | 31 kb 3′ of CTD-2245O6.1 | rs4963072 | 2.63×10−8 | 2.66×10−6 |
BRSK2 | Intronic | rs71469892 | 2.15×10−16 | 1.29×10−9 |
The rs371630624 variant at MUC5AC was excluded from this analysis as it was not supported by Sanger sequencing. #: these variants can be merged into rs71464134.