TABLE 3

Association results of 11p15.5 with or without conditioning on rs35705950

Nearby geneFunction/locationSNVUnconditioned p-valueConditioned p-value
MUC5ACMissense (Ala5353Lys)rs34474233#2.99×10−94.12×10−3
MUC5ACMissense (Ala5353Lys)rs34815853#4.15×10−96.27×10−3
MUC5B8.1 kb 5′ of MUC5Brs128029313.72×10−160.731
MUC5B/RP11-532E4.2Missense/intronicrs2002432733.55×10−81.44×10−4
CTD-2245O6.131 kb 3′ of CTD-2245O6.1rs49630734.91×10−81.48×10−6
CTD-2245O6.131 kb 3′ of CTD-2245O6.1rs49630722.63×10−82.66×10−6
BRSK2Intronicrs714698922.15×10−161.29×10−9

The rs371630624 variant at MUC5AC was excluded from this analysis as it was not supported by Sanger sequencing. #: these variants can be merged into rs71464134.