Clinical and demographic characteristics of idiopathic pulmonary fibrosis cases included in the discovery study
| University of Chicago | COMET | ACE | p-value | |
| Subjects | 138 | 22 | 21 | |
| Age years | 69±9 | 63±8 | 69±6 | 0.02 |
| Male | 108 (78.3) | 14 (63.6) | 16 (76.2) | 0.46 |
| Ever-smoker | 95 (75.4) | 17 (77.3) | 15 (71.4) | 0.91 |
| FVC % pred | 67.2±16.7 | 72.1±12.9 | 53.9±15.4 | 8.0×10−4 |
| DLCO % pred | 47.8±16.8 | 46.4±14.2 | 33.1±19.5 | 1.7×10−3 |
| Transplant | 12 (8.7) | 0 (0) | 0.17 | |
| Death | 68 (49.3) | 1 (4.5) | 3 (14.3) | 2.7×10−5 |
| Follow-up months | 38.5±24.8 | 36.3±2.8 | 35.1±4.0 | 0.41 |
| Time to death months | 27.8±17.9 | 9.57# | 4.0±2.9 | 0.06 |
Data are presented as n, mean±sd or n (%), unless otherwise stated. FVC: forced vital capacity; DLCO: diffusing capacity of the lung for carbon monoxide. #: mean.