TABLE 1

Clinical and demographic characteristics of idiopathic pulmonary fibrosis cases included in the discovery study

University of ChicagoCOMETACEp-value
Subjects1382221
Age years69±963±869±60.02
Male108 (78.3)14 (63.6)16 (76.2)0.46
Ever-smoker95 (75.4)17 (77.3)15 (71.4)0.91
FVC % pred67.2±16.772.1±12.953.9±15.48.0×10−4
DLCO % pred47.8±16.846.4±14.233.1±19.51.7×10−3
Transplant12 (8.7)0 (0)0.17
Death68 (49.3)1 (4.5)3 (14.3)2.7×10−5
Follow-up months38.5±24.836.3±2.835.1±4.00.41
Time to death months27.8±17.99.57#4.0±2.90.06

Data are presented as n, mean±sd or n (%), unless otherwise stated. FVC: forced vital capacity; DLCO: diffusing capacity of the lung for carbon monoxide. #: mean.