TABLE 1

Assignations of first-choice individual childhood interstitial lung disease (chILD) group or diagnosis in children under 2 years of age (n=35) and over 2 years of age (n=49) by 10 observers

chILD categorychILD group/diagnosisNumbers of first-choice assignations
<2 years>2 years
chILD groupsNormal318
Airways disease#77170
Interstitial pneumonia126200
Developmental/undefined aetiology disorders9948
Unclassifiable413
Bronchopulmonary dysplasia2910
Other1231
chILD DiagnosesExudative bronchiolitis42
Constrictive obliterative bronchiolitis1048
Infection4886
Chronic pneumonitis of infancy4712
Pulmonary alveolar proteinosis5324
Desquamative interstitial pneumonia813
Nonspecific interstitial pneumonia (cellular)1634
Diffuse alveolar damage38
Fibrotic nonspecific interstitial pneumonia147
Organising pneumonia030
Diffuse alveolar haemorrhage111
Alveolar microlithiasis03
Sarcoidosis06
Langerhans cell histiocytosis112
Lung growth abnormality/chronic disease of prematurity8312
Pulmonary interstitial glycogenosis110
Neuroendocrine cell hyperplasia of infancy3015
Lymphoid interstitial pneumonia123
Diffuse lymphoid hyperplasia12
Lymphomatoid granulomatosis14
Follicular bronchiolitis06
Bronchus-associated lymphoid tissue01
Primary pulmonary arterial hypertension14
PVOD/PCH35
Thromboembolic disease13
Lymphangiomatosis11
Lymphangiectasia (primary and secondary)77
Secondary vasculopathies (e.g. due to cardiac disease)62
Primary and secondary pulmonary vasculitis114
Neoplasms09
Alternate diagnosis1124

PVOD: pulmonary veno-occlusive disease; PCH: pulmonary capillary haemangiomatosis. #: airways disease included infection and obliterative and exudative bronchiolitis; : developmental/undefined aetiology disorders included growth disorders such as alveolar hypoplasia, neuroendocrine cell hyperplasia of infancy and pulmonary interstitial glycogenosis.