TABLE 1

Patient characteristics

CharacteristicsOverallUrokinaset-PA/DNAsep-value
Patients935241
Age years61.5±17.261.4±17.661.6±170.95
Males63 (68%)39 (75%)24 (59%)0.09
Right-sided effusion55 (59%)28 (54%)27 (66%)0.24
Presence of lung cancer16 (17%)7 (13%)9 (22%)0.28
Pleural fluid analyses93 (100%)
 Positive bacterial culture33 (35%)16 (31%)17 (41%)0.28
 pH7±0.47±0.26.9±0.40.63
 Glucose mmol·L−13.5±8.13.9±9.92.8±4.40.59
 Lactate dehydrogenase IU·L−12217±26762447±31711912±18310.38
Radiological findings
 Area occupied by effusion at baseline %39.4±19.638.8±2040.1±19.40.76
 CT scan86 (92%)47 (90%)39 (95%)0.39
 Number of collections2.5±1.42.4±1.42.6±1.50.46
 Isolated if ≥2 collections39 (64%)22 (71%)17 (57%)0.24
Drainage
 Image-guided procedure76 (82%)38 (73%)38 (93%)0.02
 Tube size French13.7±414.5±4.812.6±2.40.02
 Hospitalisation-to-drainage duration days3 (1–8)2 (0–7)3 (2–9)0.31
 Drainage-to-lysis duration days1 (0–2)1 (0–2)1 (0–2)0.23

Data are presented as mean±sd or median (interquartile range), unless otherwise stated. t-PA: tissue plasminogen activator; CT: computed tomography.