Cognitive function assessment before and after the pulmonary rehabilitation (PR) programme in the 24 lung transplantation recipients

Domain-specific evaluationPre-PRPost-PRMean differenceESp-value
Memory ability
 WMS Logical Memory I score11.0±2.712.9±2.41.9±2.70.760.004
 WMS Logical Memory II score9.7±3.011.9±3.82.2±2.90.660.003
 CVLT Free recall: list 1 score30.4±28.251.7±34.721.3±28.50.690.003
 CVLT Free recall: list 2 score33.3±31.147.8±34.114.5±26.00.450.022
 CVLT Recall with help: list 1 score38.7±26.650.9±33.612.2±31.60.41ns
 CVLT Recall with help: list 2 score38.5±28.750.7±30.912.2±23.90.420.034
 CVLT Repeating errors score68.6±21.870.9±27.52.3±26.40.09ns
 Composite score32.7±29.242.1±33.69.3±23.60.310.001
Learning skills
 CVLT Learning ability %33.4±31.857.1±33.923.7±28.20.740.020
 CVLT Passage 1 %32.1±23.461.0±34.228.9±
 CVLT Passage 5 %20.8±25.440.3±34.619.5±24.20.660.001
 CVLT List B %23.0±28.425.6±22.02.6±28.20.10ns
 Composite score27.5±27.546.4±34.218.9±30.40.620.001
Attention and flexibility
 TAP Speed/accuracy %56.2±31.556.5±32.90.3±27.60.01ns
 TAP Shared attention ability %50.4±28.345.8±28.9−4.6±33.00.16ns
 Composite score54.1±29.851.3±31.1−2.8±30.10.09ns
Visuospatial and processing speed
 TMT-A score42.8±14.938.3±20.1−4.5±27.90.26ns
 TMT-B score99.0±52.284.9±35.2−14.1±36.90.32ns
 Composite score70.9±47.461.6±36.9−9.3±32.70.22ns
Visuospatial and praxis ability
 CDT Clock test score13.1±1.213.1±1.30.0±0.70.01ns
Psychomotor speed
 Stroop colour-word read points48.5±7.551.3±7.72.8±4.90.380.015
 Stroop colour recognition points54.4±8.157.4±9.33.0±6.00.350.027
 Stroop interference points55.0±9.755.3±9.30.3±7.70.03ns
 Composite score52.6±8.854.6±9.02.0±
Behavioural activation
 BADS version 1 score6.8±1.66.1±1.6−0.7±2.60.42ns
 BADS version 2 score7.6±0.77.6±0.7−0.0±0.90.01ns
 Composite score7.1±1.36.8±1.4−0.3±1.90.23ns

Data are presented as mean±sd, unless otherwise stated. ES: effect size; WMS: Wechsler Memory Scales IV; CVLT: California Verbal Learning Test; TAP: Test of Attentional Performance; TMT: Trail Making Test; CDT: Clock-Drawing Test; BADS: Behavioural Assessment of the Dysexecutive Syndrome. Positive values (better scores) determine improvement for memory ability, learning skills, psychomotor speed (points) and visuospatial/praxis ability, while negative values (faster responses) determine improvement (expressed as positive ES) for behavioural activation, visuospatial and processing speed, and attention/flexibility. Level of significance was set at p≤0.05; ns: nonsignificant.