TABLE 1

Descriptive statistics among female twins with and without polycystic ovary syndrome (PCOS)

Non-PCOSPCOSCrude OR (95% CI)p-valueAdjusted OR (95% CI)#p-value
Subjects32 279103
Age¶,+ years31±18.922±8.20.92 (0.88–0.93)<0.0010.99 (0.99–0.99)0.004
BMI kg·m−2 (n=29 195)
 <18.5 (underweight)1269 (4)3 (3)0.38 (0.05–2.80)0.351.13 (0.89–1.44)0.33
 18.5–24.9 (normal weight)21 019 (72)66 (68)ReferenceReference
 25.0–29.9 (overweight)5151 (18)13 (13)0.98 (0.50–1.92)0.961.35 (1.19–1.54)<0.001
 ≥30.0 (obese)1659 (6)15 (16)3.58 (1.94–6.66)<0.0011.92 (1.61–2.28)<0.001
Alcohol units·week−1 (n=20 053)
 Never3678 (18)11 (18)ReferenceReference
 1–611 427 (57)39 (63)1.14 (0.58–2.23)0.700.88 (0.77–1.00)0.06
 7–133392 (17)12 (19)1.18 (0.52–2.68)0.690.89 (0.75–1.05)0.16
 14–201101 (6)0 (0)0.000.990.92 (0.72–1.17)0.45
 ≥21393 (2)0 (0)0.000.991.00 (0.69–1.44)0.99
Smoking status (n=21 839)
 Never-smoker9883 (45)42 (63)ReferenceReference
 Ex-smoker4267 (20)8 (12)0.44 (0.21–0.94)0.041.38 (1.21–1.58)<0.001
 Current smoker7622 (35)17 (25)0.53 (0.30–0.92)0.031.19 (1.06.–1.33)0.004
Asthma2959 (9)18 (18)2.11 (1.13–3.96)0.021.56 (0.76–3.19)0.23

Data are presented as n, mean±sd or n (%), unless otherwise stated. BMI: body mass index. #: adjusted for age, BMI, alcohol and smoking; : age when filling in the questionnaire; +: OR for age measured per year. Within black box: univariate logistic regression; outside black box: multivariate logistic regression. p<0.05 considered significant.