Baseline characteristics of patients who underwent transbronchial lung cryobiopsy in the context of an interstitial lung disease diagnostic work-up
Total | HLS | PS | ULS | |
Male | 19 (59.4) | 11 (52.4) | 6 (100) | 2 (40) |
Age years | 47.7±12.6 | 44.5±11 | 46±11.3 | 62.8±11.1 |
Pulmonary function test | ||||
FVC % pred | 98.3±21.5 | 92.1±18.6 | 105.6±22.2 | 115.5±24.5 |
FEV1% pred | 94.4±21.2 | 87.7±17.5 | 105.3±24.1 | 109.7±22.8 |
FEV1/FVC | 77.9±7.0 | 77.4±8.2 | 79.8±4.9 | 77.5±3.8 |
DLCO % pred | 76.3±18.6 | 72.5±17.1 | 91±19 | 79.3±21.2 |
DLCO/VA % pred | 88.6±18.8 | 84.3±13.5 | 112.5±22.6 | 85±21.3 |
BAL results | ||||
Lymphocytes % | 33.7±16.2 | 37.2±16.3 | 22.9±14.4 | 32±14 |
Neutrophils % | 2.9±3.2 | 2.1±1.7 | 5.6±5.9 | 3±2.5 |
Eosinophil % | 0.5±0.7 | 0.4±0.7 | 0.7±0.7 | 0.6±0.7 |
CD4/CD8 ratio | 3.2±3.0 | 3.3±3.5 | 3.4±1.7 | 2±1.3 |
Chest CT findings | ||||
Micronodularity | 25 (78.1) | 17 (81) | 6 (100) | 2 (40) |
Adenopathy | 10 (31.3) | 9 (42.9) | 1 (16.7) | 0 |
Consolidation | 2 (6.3) | 2 (9.5) | 0 | 0 |
Air trapping/mosaic pattern | 2 (6.3) | 0 | 0 | 2 (40) |
Ground glass | 2 (6.3) | 1 (4.8) | 0 | 1 (20) |
Fibrosis | 1 (3.2) | 1 (4.8) | 0 | 0 |
Data are presented as n (%) or mean±sd. HLS: highly likely sarcoidosis; PS: possible sarcoidosis; ULS: unlikely sarcoidosis; FVC: forced vital capacity; FEV1: forced expiratory volume in 1 s; DLCO: diffusing capacity of the lung for carbon monoxide; DLCO/VA: DLCO adjusted for alveolar volume; BAL: bronchoalveolar lavage; CT: computed tomography.