TABLE 3

Storage conditions for common medications for bronchiectasis

Drug nameCommon trade names in EuropeStorage conditionsComments
Oral antibiotics and antifungals
  AzithromycinCap. azithromycin 250 mg
Cap. Azenil 250 mg
Cap. azithromycin Inovamed 250 mg
Cap. Zithromax 250 mg
Tab. Zeto 250 mg
Tab. azithromycin 250 mg
Cap., tab.: store in the original package in order to protect from light; store below 25°CSkin photosensitivity: uncommon (≤1%)
Alcohol: no special recommendation
Azenil 200 mg/5 mL powder for oral susp.
Azithromycin 200 mg/5 mL powder for oral susp.
Azithromycin Teva 200 mg/5 mL powder for oral susp.
Zithromax 200 mg/5 mL powder for oral susp.
Powder for susp.: store below 25°C
Reconstituted susp.: store at room temperature, below 25°C
After reconstitution of the powder, use the susp. within 5 days; shake immediately prior to use
  ErythromycinTab. erythromycin 250 mg
Tab. Erythro Teva 250 mg; 500 mg
Tab. Erythrocin 250 mg; 500 mg
Tab. Erythroped A 500 mg
Tab.: store in a dry place, below 25°CAlcohol: may decrease the absorption of erythromycin or enhance effects of alcohol (ethanol); the combination should be avoided
Erythromycin SF granules for oral susp. 125 mg/5 mL; 250 mg/5 mL; 500 mg/5 mL
Erythromycin ethyl succinate granules for oral susp. 125 mg/5 mL; 250 mg/5 mL; 500 mg/5 mL
Erythroped SF 250 mg/5 mL; 500 mg/5 mL
Primacine granules for oral susp. 250 mg/5 mL
Granules for susp.: store below 25°C
Reconstituted susp.: store in a refrigerator (2–8°C); do not freeze
After reconstitution, use the suspension within 14 days; shake immediately prior to use
  RoxithromycinTab. Rulid 150 mg; 300 mg
Tab. Roxo 150 mg
Tab.: store below 25°CAlcohol: no special recommendation
  ClarithromycinTab. Karin 250 mg, 500 mg
Tab. Klacid SR 500 mg
Tab. clarithromycin 250 mg, 500 mg
Tab. Klaricid XL 500 mg
Prolonged release tab. Mycifor XL 500 mg
Caplets Klaridex 250 mg
Tab., caplets: store in the original package in order to protect from light and moisture; store below 25°C (some manufacturers permit excursions up to 30°C)Alcohol: no special recommendation
Sachet Klaricid adult 250 mgSachet: store in a dry place, below 30°C
Mix the contents of the sachet with a small amount of water before taking to make the granules easier to swallow
Klacid paediatric granules for susp. 125 mg/5 mL
Susp. Clarithromycin 125 mg/5 mL; 250 mg/5 mL
Oral susp. clarithromycin 125 mg/5 mL; 250 mg/5 mL
Klaricid paediatric susp. 125 mg/5 mL; 250 mg/5 mL
Granules for susp.: store below 30°C
Reconstituted susp.: store at room temperature, below 25°C (up to 30°C according to manufacturer) and use within 14 days from reconstitution; do not refrigerate or freeze the reconstituted suspension; shake immediately prior to use
  AmoxicillinCap. amoxicillin 250 mg; 500 mg
Cap. Amoxil 250 mg; 500 mg
Cap. Moxyvit 250 mg
Cap. Moxyvit forte 500 mg
Cap. Moxypen forte 500 mg
Cap.: store in a dry place, below 25°CAlcohol: no special recommendation
Amoxicillin powder for oral susp. 125 mg/5 mL; 250 mg/5 mL
Amoxicillin powder for oral susp. SF 125 mg/5 mL; 250 mg/5 mL
Moxyvit forte powder for oral susp. 250 mg/5 mL
Moxypen forte powder for susp. 250 mg/5 mL
Powder for susp.: store in a dry place, below 25°C
Reconstituted susp.: according to manufacturer instructions, store in a refrigerator (2–8°C) or at room temperature (below 25°C) and use within 7–14 days#; shake immediately prior to use
  Amoxicillin–clavulanic acidTab. Amoxiclav Teva 875 mg
Tab. Augmentin 250 mg; 500 mg; 875 mg
Tab. co-amoxiclav 250 mg; 500 mg
Tab. Maclivan 500 mg
Tab.: store in the original package in order to protect from moisture; store below 25°C
Augmentin tab. supplied in an aluminium pouch should be used within 30 days of opening the pouch
Alcohol: no special recommendation
Augmentin powder for oral susp. 250 mg/5 mL; 400 mg/5 mL
Augmentin ES Augmentin powder for oral susp. 600 mg/5 mL
Co-amoxiclav powder for oral suspension 125 mg/5 mL; 250 mg/5 mL; 400 mg/5 mL
Maclivan powder for oral suspension 250 mg/5 mL; 400 mg/5 mL
Powder for susp.: store in the original package in order to protect from moisture; store below 25°C
Reconstituted susp.: according to manufacturer instructions, store in a refrigerator (2–8°C) and use within 7–10 days#
  DoxycyclineCap. Doxy 100 mg
Cap. doxycycline 50 mg; 100 mg
Cap. Vibramycin Hyclate 100 mg
Tab. Doxylin 100 mg
Vibramycin-D 100 mg Dispersible tabs
Vibra-Tabs 100 mg
Cap., tab.: store in the original package in order to protect from light and moisture; store below 25°C#Skin photosensitivity: sunlight or ultraviolet light exposure increases the risk of photosensitivity; use skin protection and avoid prolonged exposure to sunlight and ultraviolet light; avoid use of tanning equipment.
Discontinue the treatment at first sign of skin erythema
Alcohol: ingestion may shorten the half-life of doxycycline and reduce its serum concentration; the combination should be avoided
Doxycycline powder for susp. 25 mg/5 mL
Vibramycin monohydrate powder for susp. 25 mg·mL−1
Powder for susp.: store in the original package in order to protect from light and moisture; store below 25°C#
Reconstituted susp.: store in the original package in order to protect from light and moisture; store below 25°C (up to 30°C according to manufacturer); use within 14 days from reconstitution; shake immediately prior to use
Vibramycin calcium syrup 50 mg·mL−1Syrup: store in the original package in order to protect from light and moisture; store below 30°C
  MinocyclineCap. minocycline 50 mg; 100 mg
Cap. Minoclin 100 mg
Tab. minocycline 50 mg; 100 mg
Cap., tab.: store in the original package in order to protect from light; store below 25°CSkin photosensitivity: may cause photosensitivity; use skin protection and avoid prolonged exposure to sunlight and ultraviolet light; avoid use of tanning equipment
Discontinue the treatment if skin erythema occurs
Alcohol: no special recommendation
  CefuroximeTab. Zinnat 125 mg; 250 mg; 500 mg
Tab. Cefuroxime 250 mg
Tab. store in the original package in order to protect from moisture; store below 30°CAlcohol: no special recommendation
Zinnat powder for oral susp. 125 mg/5 mL; 250 mg/5 mLPowder for suspension: store in the original package, below 30°C
Reconstituted susp.: store in a refrigerator (2–8°C); do not freeze
After reconstitution, use the susp. within 10 days; shake the bottle vigorously before the medication is taken
  CephalexinCap. Cefovit 250 mg; forte 500 mg
Cap., tab. Cefalexin 250 mg; 500 mg
Tab. Keflex 250 mg; 500 mg
Cap.: store in a dry place, below 25°CAlcohol: no special recommendation
Cefovit powder for oral susp. 125 mg/5 mL;
Cefovit forte 250 mg/5 mL
Cefalexin granules for oral susp. 125 mg/5 mL; 250 mg/5 mL
Keflex granules for oral susp. 125 mg/5 mL; 250 mg/5 mL
Powder/granules for susp.: store in a dry place, below 25°C
Reconstituted susp.: according to manufacturer instructions, store in a refrigerator (2–8°C) and use within 10–14 days#; shake well before each use
  SMX-TMPCaplets Diseptyl forte 800 mg/160 mg
Tab. co-trimoxazole 400 mg/80 mg
Tab. co-trimoxazole forte 800 mg/160 mg
Tab. Septrin 400 mg/80 mg
Tab. Septrin forte 800 mg/160 mg
Cap., tab.: store in the original package, below 25°CSkin photosensitivity: as been reported with SMX-TMP; use with caution; use skin protection and avoid prolonged exposure to sunlight and ultraviolet light; avoid use of tanning equipment
Discontinue the treatment if skin erythema occurs
Alcohol: a disulfiram-like reaction (flushing, sweating, palpitations and drowsiness) may occur if alcohol (0.5–1 L of an alcoholic drink e.g. beer) is ingested
Susp. Diseptyl 200 mg/40 mg in 5 mL
Co-trimoxazole paediatric susp. 200 mg/40 mg in 5 mL
Co-trimoxazole adult susp. 400 mg/80 mg in 5 mL
Septrin paediatric susp. 200 mg/40 mg in 5 mL
Septrin adult susp. 400 mg/80 mg in 5 mL
Susp. Store in a dark and dry place, below 25°C
Use within 10 days of opening#.
  CiprofloxacinTab. Ciprodex 250 mg; 500 mg; 750 mg
Tab. ciprofloxacin Teva 250 mg; 500 mg; 750 mg
Ciprofloxacin 100 mg; 250 mg; 500 mg; 750 mg film-coated tab.
Tab. Ciproxin 500 mg
Tab. store in the original package, below 25°CSkin photosensitivity: ciprofloxacin has been shown to cause photosensitivity reactions; use skin protection and avoid prolonged exposure to sunlight and ultraviolet light; avoid use of tanning equipment
Discontinue the treatment if skin erythema occurs
Caffeine: ciprofloxacin has been shown to interfere with the metabolism of caffeine leading to increased caffeine concentrations; patients consuming regular large quantities of caffeinated beverages may need to restrict caffeine intake if excessive cardiac or central nervous system stimulation occurs; the effect of this interaction is greater in females
Ciproxin 250 mg/5 mL, granules and solvent for oral susp.Ciproxin: store the granules and solvent below 25°C; protect the solvent from freezing; avoid inverted storage
The ready-to-use oral susp. (utilising the individual components) is stable only for 14 days when either stored in a refrigerator (2–8°C) or at temperatures up to 30°C; protect the reconstituted susp. from freezing
  MoxifloxacinTab. Megaxin 400 mg
Tab., film-coated Moxicloxacin 400 mg
Tab. Avelox 400 mg
Tab.: store in the original package in order to protect from moisture; store below 25°CSkin photosensitivity: quinolones have been shown to cause photosensitivity reactions in patients; use skin protection and avoid prolonged exposure to sunlight and ultraviolet light; avoid use of tanning equipment
Discontinue the treatment if skin erythema occurs
  FluconazoleCap. Flucanol 50 mg; 100 mg; 150 mg; 200 mg
Cap. fluconazole Teva 150 mg
Cap. Trican 50 mg, 100 mg, 150 mg, 200 mg
Cap. fluconazole/Azocan 50 mg, 150 mg, 200 mg
Cap.: store in a dry place below 25°C#Alcohol: no special recommendation
Fluconazole powder for oral susp. (Genus Pharmaceuticals) 50 mg/5 mL
Diflucan powder for oral suspension 10 mg/mL; 40 mg/mL
Powder for susp.: store in a dry place, below 25°C
Reconstituted susp. store in a refrigerator (2–8°C) or at temperatures up to 30°C use within 14–28 days#; protect the reconstituted susp. from freezing; shake well before administration
  ItraconazoleCap. Itranol 100 mg
Cap. itraconazole 100 mg
Cap.: store in the original package in order to protect from moisture; store below 25°CSkin photosensitivity: uncommon (≤2%); case reports have been described
Use skin protection and avoid prolonged exposure to sunlight and ultraviolet light; avoid use of tanning equipment
Discontinue the treatment if skin erythema occurs
Alcohol: no special recommendation
Cap. SporanoxSporanox cap.: up to 30°C
Sporanox oral solution 10 mg·mL−1Powder for susp.: store below 25°C; use within 30 days of opening
Itraconazole 10 mg·mL−1 oral solution
Expectorants and cough suppressants
  AcetylcysteineReolin effervescent tablets 200 mg
Siran 200 mg effervescent tablets
Effervescent tablets: store in the original package in order to protect from moisture; store below 25°C; close the tube immediately after taking out the tablet
After dissolving the tablet, it must be used immediately
Reolin: use within 2 years after the first opening or until the expiry date
Siran: use within 4 weeks after the first opening
Alcohol: no special recommendation
Sachet acetylcysteine 200 mg powder for oral solutionPowder for oral solution: store in the original package in order to protect from moisture
Reconstituted solution: the product must be used immediately
GuaifenesinResyl syrup 100 mg/5  mL (contains 6% alcohol by volume)
Benylin syrup for children's chesty coughs 50 mg/5 mL
Benylin syrup Mucus Cough Max honey and lemon flavour 100 mg/5 mL (contains 4.7% alcohol by volume)
Oral solution Benylin Mucus Cough Max menthol flavour 100 mg/5 mL (contains 4.7% alcohol by volume)
Boots chesty cough relief 100 mg/5 mL oral solution
Boots chesty cough syrup 6 years plus (contains alcohol)
Boots mucus cough relief 100 mg/5 mL oral solution
Covonia chesty cough SF syrup
Robitussin chesty cough medicine 100 mg/5mL−1 oral solution (contains 2.7% v/v alcohol)
Lemsip cough for chesty cough 50 mg/5 mL oral solution
Syrup: store in the original package, below 25°C
Resyl: store below 30°C; use within 6 months of opening
Benylin honey and lemon flavour: use within 6 months of opening
Oral solution: store below 25°C
Benylin menthol flavour: store in the original container to protect from light and use within 4 weeks of opening
Alcohol: some products contain alcohol; therefore, these formulations can emphasise the effect of sedatives (including alcohol) and myorelaxants
Avoid concurrent use or use caution when motor skills are required
Other oral medications
  PrednisoneTab. prednisone 1 mg; 5 mg; 20 mg
Modified-release tab. Lodotra 1 mg; 2 mg; 5 mg
Tab.: store in a dark and dry place, below 25°C
Tab. prednisone 1 mg: use within 2 months of opening (but not after the expiry date)
Lodotra: store below 25°C and use within 14 weeks of opening (but not after the expiry date)
Alcohol: no special recommendation
  PrednisoloneTab. Pevanti 2.5 mg; 5 mg; 10 mg; 20 mg; 25 mg
Tab. prednisolone 1 mg, 2.5 mg; 5 mg; 10 mg; 20 mg; 25 mg; 30 mg
Tab. prednisolone gastro-resistant 1 mg; 2.5 mg; 5 mg
Soluble tab. prednisolone 5 mg
Tab. (also gastro-resistant and soluble tab.): store in the original package in order to protect from light and moisture, below 25°C
Pevanti: use within 6 months of opening (but not after the expiry date)
Alcohol: some products contain alcohol; avoid concurrent use of ethanol with these formulations or use caution when motor skills are required
Danalone syrup 15 mg/5 mL (contains alcohol)Syrup: store below 25°C but not in the refrigerator; close firmly, and prevent penetration of air and moisture
Prednisolone Dompe 1 mg·mL−1 oral solution (single-dose containers)
Prednisolone 10 mg·mL−1 oral solution
Dompe: before opening, store in the original package; store below 30°C
Once opened, the container must be discarded once the dose is removed
Prednisolone 10 mg·mL−1: keep the container in the outer carton in order to protect from light
Before opening, store in a refrigerator (2–8°C)
Once opened, store below 25°C and use within 3 months
  Proton pump inhibitors
   OmeprazoleCaplets Omepradex 10 mg; 20 mg; 40 mg
Caplets Omepradex-Z 20 mg
Caplets: store in the original package, below 25°CSkin photosensitivity: has been described but is rare (≤0.1%)
Alcohol: no special recommendation
Cap. Losec 20 mg (Israel)
Cap. Omepra 10 mg; 20 mg; 40 mg
Cap. Omeprix 20 mg
Cap. Losec 10 mg; 20 mg; 40 mg (Europe)
Cap. Mepradec gastro-resistant 10, 20 mg
Cap. Omeprazole gastro-resistant 10 mg; 20 mg; 40 mg
Cap. Prenome 10 mg; 20 mg; 40 mg
Cap. Omeprazole 10 mg; 20 mg; 40 mg
Tab. Omeprazole Gastro-resistant 10 mg; 20 mg; 40 mg
Pyrocalm Control 20 mg gastro-resistant tablets
Cap., tab.: store below 25°C
Store in the original package in order to protect from moisture, below 25–30°C and use within 3 months of opening of the bottle#
   EsomeprazoleTab. esomeprazole Inovamed 20 mg; 40 mg
Tab. Nexium 20 mg; 40 mg
Tab. esomeprazole gastro-resistant 20 mg; 40 mg
Cap. Emozul gastro-resistant 20 mg, 40 mg
Cap. esomeprazole gastro-resistant 20 mg; 40 mg
Ventra gastro-resistant capsules 20 mg; 40 mg
Tab., cap.: store in the original package in order to protect from moisture
Store below 25–30°C# and use within 3–6 months after first opening of the bottle#
Skin photosensitivity: has been described in the literature but is rare (≤0.1%)
Alcohol: no special recommendation
Sachet Nexium 10 mg gastro-resistant granules for oral susp.Granules for oral susp.: use within 30 min after reconstitution
   LansoprazoleCap. lansoprazole 15 mg; 30 mg
Cap. Lanton 15 mg; 30 mg
Cap. lansoprazole gastro-resistant 15 mg; 30 mg
Orodispersible tab. lansoprazole 15 mg; 30 mg
Zoton Fas-Tab 15 mg; 30 mg
Cap., tab.: store in the original package in order to protect from light and moisture; store below 25°C
Use within 2 months to 100 days after first opening of the bottle#
Skin photosensitivity: has been described in the literature but is rare (≤0.1%)
Alcohol: no special recommendation
   PantoprazoleTab. Contrololc 20 mg; 40 mg
Pantoloc Control 20 mg gastro-resistant tablets
Tab. Pantoprazole gastro-resistant 20 mg; 40 mg
Tab. store in the original package in order to protect from moisture; store below 25°C
Use within 6 months after first opening of the bottle#
Skin photosensitivity: has been described in the literature (but the frequency cannot be estimated from the available data); use with caution
Alcohol: no special recommendation
  H2 blockers
   FamotidineTab. famotidine Teva 20 mg; 40 mg
Tab. Famo 20 mg; 40 mg
Tab. Gastro 10 mg; 20 mg; 40 mg
Tab. Pepcid 20 mg; 40 mg
Tab. store in the original package in order to protect from light and moisture; store below 25°CAlcohol: no special recommendation
Pepcid powder for oral susp. 40 mg/5 mLPowder for susp.: store in the original package at 25°C; excursions permitted to 15–30°C
Reconstituted susp.: after reconstitution, use the suspension within 30 days; protect from freezing
   RanitidineTab. Zaridex 150 mg; 300 mg
Tab. Ranitidine film-coated 150 mg; 300 mg
Tab. Zantac 75 mg; 150 mg; 300 mg
Tab.: store in the original package, below 25°CAlcohol: co-ingestion of alcohol (1.5–2 drinks) while on ranitidine may result in higher blood alcohol concentrations, although the clinical significance is uncertain
In addition, some products contain alcohol; avoid concurrent use of ethanol with these formulations or use caution when motor skills are required
Zantac syrup 150 mg/10 mL (contains ∼7.5% w/v alcohol)Syrup: store below 25°C and use within 28 days of opening
Ranitidine 150 mg/10 mL oral solution (contains ∼8% w/v alcohol)
Ranitidine 30 mg·mL−1 oral solution (contains ∼7.5% w/v alcohol)
Oral solution: store in original carton/bottle in order to protect from light; store below 25°C
  Antacids
   Aluminium hydroxide,   magnesium hydroxide and   dimethicone/simethiconeMaalox Plus chewable tablets (200 mg magnesium hydroxide, 200 mg hydrated aluminium oxide and 25 mg dimethicone in a tablet)Tab.: store in the original package, below 25°CAlcohol: no special recommendation
Maalox Plus oral susp. (225 mg aluminium hydroxide, 200 mg magnesium hydroxide and 25 mg simethicone in 5 mL)Oral susp.: store below 25°C and use within 28 days of opening; shake well before administration
   Calcium carbonateChewable tab. Tums
Chewable tab. N-Zarevet
Chewable tab.
Chewable tab.: store in the original package, below 25°C
N-Zarevet: use within 12 months after first opening of the bottle
Alcohol: no special recommendation
   Calcium carbonate and   magnesium carbonateChewable tab. Rennie
Chewable tab. Rolaids
Chewable tab.: store in the original package, below 25°CAlcohol: no special recommendation
Rolaids mint liquid (550 mg calcium carbonate and 110 mg magnesium hydroxide in 5 mL)Liquid: do not freeze
   Calcium carbonate, sodium   bicarbonate and sodium   alginateChewable tab. GavisconChewable tab.: store in the original package in order to protect from moisture; below 25–30°C#Alcohol: no special recommendation
Gaviscon peppermint liquidLiquid: store in the original package, below 25–30°C (according to manufacturer instructions) and use within 6 months of opening
Gaviscon liquid sachets mint flavour (500 mg sodium alginate, 267 mg sodium bicarbonate and 160 mg calcium carbonate per 10-mL dose)Liquid sachet: store in the original package, below 25°C; discard any unused contents
Bronchodilators: inhalers and solution
  Salbutamol MDIVentolin inhaler CFC-Free 100 µg per dose
Salbutrim CFC-free inhaler 100 µg per dose
Ventolin, Salbutrim: store below 30°C; protect from frost and direct sunlight
If the inhaler gets very cold, take the metal container out of the plastic case and warm it in your hands for a few minutes; do not use anything else to warm it up
Alcohol: no special recommendation
Easyhaler Salbutamol 100 µg per dose, 200 µg per dose
Salamol Easi-Breathe 100 µg per dose
Easyhaler: store in a dry place, at a temperature below 25°C; use within 6 months after first opening of foil pouch
Salbulin MDPI NovolizerSalbulin: store below 30°C; use within 6 months after first opening the container
  Ipratropium MDIMDI Atrovent 20 µg per doseMDI: store below 25°C (Europe) or 30°C (Israel); protect from frost and direct sunlight; do not expose to temperature >50°CAlcohol: no special recommendation
  Salbutamol (solution)Ventolin respirator solution 5 mg·mL−1 (0.5% w/v)Ventolin respirator solution: store below 25–30°C#; protect from light; discard any contents remaining 1 month after opening the bottle
A fresh solution should be prepared before each usage
Alcohol: no special recommendation
Ventolin Nebules 2.5 mg/2.5 mL (0.1% w/v), 5 mg/2.5 mL (0.2% w/v)
Ampules Salbutamol 2.5 mg/2.5 mL nebuliser solution; 5 mg/2.5 mL
Ventolin Nebules, Ampules Salbutamol: store below 25–30°C#; protect from light after removal from the foil overwrap pouch
Use nebules 3 months after removal from the foil pouch; use immediately after first opening of the ampule and discard any unused contents
  Ipratropium (solution)Aerovent respirator solution 0.25 mg·mL−1Respirator solution: store below 25°C; do not freeze
Discard any contents remaining 1 month after opening the bottle
A fresh solution should be prepared before each usage
Alcohol: no special recommendation
Atrovent 250 UDVs, 1 mL; Atrovent UDVs, 2 mL–0.25 mg·mL−1 vials
Ampules ipratropium bromide 250 µg/1 mL nebuliser solution; 500 µg/2 mL nebuliser solution
Atrovent 250 UDVs, Atrovent UDVs, Ampules Ipratropium bromide: keep the vials in the outer carton; store below 25°C
Use immediately after first opening of the ampule and discard any unused contents
Other inhaled medications
  Isotonic saline (sodium  chloride 0.9% w/v)Ampules sodium chloride 0.9% Fresenius 5 mL; 10 mL; 20 mL per ampule
Saline nebuliser solution Arrow 2.5 mL per ampule
Saline Steripoules 2.5 mL
Ampules: store below 25°C; do not refrigerate or freeze
Saline nebuliser solution
Strips of 10 ampules are overwrapped in an aluminium foil pack; ampules removed from the foil overwrap should be used within 90 days
Alcohol: no special recommendation
  Hypertonic saline (sodium  chloride 3%, 6%, 7% w/v)INH Solution MucoClear (sodium chloride) 3%, 4 mL per ampule
INH Solution MucoClear (sodium chloride) 6%, 4 mL per ampule
MucoClear: store below 25°C; do not refrigerate or freezeAlcohol: no special recommendation
INH Solution PulmoSal 7%, (pH+) 4 mL per vialPulmosal: store at room temperature, 15–30°C; avoid excessive heat and protect from freezing
Inhaled antimicrobials
  CMSVial Coliracin 1 000 000 units per vial
Vial CMS 1 000 000 IU powder for solution for injection
Vial Colomycin 1 000 000 IU, 2 million IU
Promixin, 1 000 000 IU powder for nebuliser solution
Vial: store below 25°C; protect from light
Use immediately after reconstitution with 0.9% sodium chloride; solutions may be used within 24 h when stored in a refrigerator (2–8°C)
Alcohol: no special recommendation
Colobreathe 1 662 500 IU inhalation powder, hard capsules (∼125 mg CMS)Colobreathe: store in the original package until immediately before use in order to protect from moisture; store below 25°C
  TobramycinVial tobramycin 40 mg·mL−1 solution for injectionVial for injection: store in the outer carton in order to protect from light; store below 25°C
Use immediately after reconstitution with 0.9% sodium chloride
Solutions may be used within 24 h when stored in a refrigerator (2–8°C)
A fresh solution should be prepared before each usage
Alcohol: no special recommendation
Vial Nebcin injection 40 mg·mL−1Ready-to-use nebuliser solution: store in the original package in order to protect from light and moisture; store in a refrigerator (2–8°C); do not freeze
Bramitob 300 mg/4 mL nebuliser solution, single-dose containerThe contents of the whole ampule should be used directly after opening; opened ampules should never be stored for re-use
TOBI Podhaler 28 mg per capsule inhalation powder, hard capsulesTOBI pouch, Tymbrineb foil pouch, Tobramycin pouch (intact or opened); may be stored at room temperature (up to 25°C) for up to 28 days
TOBI 300 mg/5 mL nebuliser solution, single-use ampuleBramitob bags (intact or opened) may be stored at room temperature (up to 25°C) for up to 3 months
Vantobra pouch (intact or opened) may be stored at room temperature (up to 25°C) for up to 4 weeks
TOBI Podhaler 28 mg per capsule inhalation powderCapsules for inhalation: TOBI Podhaler capsules must always be stored in the blister to protect from moisture and only removed immediately before use; store below 30°C
Podhaler device: store the inhaler in its tightly closed case when not in use; each Podhaler device and its case are used for 7 days and then discarded and replaced
  GentamicinAmpule gentamicin B. Braun 1 mg·mL−1; 3 mg·mL−1 solution for infusion
Ampule gentamicin 10 mg·mL−1 solution
Ampule Genticin 40 mg·mL−1 injectable
Ampule Cidomycin 80 mg/2 mL solution for injection
Ampules for injection: store in the outer carton in order to protect from light; store below 25°C; use immediately after reconstitution with 0.9% sodium chloride; a fresh solution should be prepared before each usageAlcohol: no special recommendation

Cap: capsules; tab: tablets: susp.: suspension; SF: sugar free; SR: sustained release; SMX: sulfamethoxazole; TMP: trimethoprim; MDI: metered-dose inhaler; CFC: chlorofluorocarbon; CMS: colistimethate sodium.#: see leaflet, as different instructions for different manufacturers [23].