TABLE 7

Factors associated with time to starting treatment from symptom onset

Crude HR (95% CI)Age-adjusted HR (95% CI)Fully adjusted HR (95% CI)#
Age0.98 (0.98–0.99)0.98 (0.98–0.99)
Sex (male versus female)1.22 (1.04–1.43)1.23 (1.05–1.46)0.85 (0.72–1.00)
Ethnic group0.98 (0.94–1.02)0.98 (0.95–1.02)
UK born0.92 (0.67–1.27)1.23 (1.05–1.46)1.05 (0.77–1.43)
Sputum smear0.98 (0.90–1.07)0.97 (0.88–1.06)
TB sensitivity1.14 (0.99–1.32)0.98 (0.82–1.18)
HIV1.37 (0.93–2.02)2.07 (1.30–3.29)0.71 (0.46–1.07)
Diabetes1.55 (1.21–1.99)1.26 (0.97–1.64)
Hypertension1.40 (1.13–1.73)1.14 (0.90–1.44)
Renal failure1.22 (0.99–1.51)1.11 (0.86–1.45)
Cancer1.27 (0.82–1.98)
Lung disease
 Asthma/COPD1.78 (0.67–4.69)
 Bronchiectasis2.26 (0.74–6.90)
 ILD1.41 (0.32–6.16)
 PE5.64 (1.87–17.01)
 Sarcoid28.2 (5.91–124.76)
PTB versus EPTB1.01 (0.93–1.30)
Cough1.07 (0.91–1.25)
Sweats1.22 (1.03–1.44)1.15 (0.97–1.37)
Weight loss0.90 (0.77–1.05)

HR: hazard ratio; TB: tuberculosis; COPD: chronic obstructive pulmonary disease; ILD: interstitial lung disease; PE: pulmonary embolism; PTB: pulmonary tuberculosis; EPTB: extrapulmonary tuberculosis. #: adjusted for age, sex, UK born and HIV.