Radiological abnormality scores for cases without alternative causes of bronchiectasis according to human T-cell leukaemia virus type 1 (HTLV-1) pro-viral load (PVL)
| Low PVL (<1000 copies per 105 PBLs) | High PVL (≥1000 copies per 105 PBLs) | p-value# | |
| Subjects | 19 | 12 | |
| Bronchiectasis score | 4.53±3.67 | 7.25±3.86 | 0.039 |
| Bronchial wall thickening | 3.74±3.14 | 6.17±3.01 | 0.038 |
| Cystic bronchiectasis | 0.68±1.25 | 1.67±1.37 | 0.028 |
| Saccular bronchiectasis | 0.50±0.99 | 1.47±1.55 | 0.025 |
| Ground-glass opacities | 0.85±0.96 | 1.75±1.71 | 0.144 |
| Mucus plugging/centrilobular nodules | 1.21±1.47 | 1.83±1.58 | 0.248 |
| Total radiology abnormality score¶ | 11.68±8.56 | 20.33±9.78 | 0.022 |
Data are presented as n or mean±sd, unless otherwise stated. PBL: peripheral blood leukocyte. Combined radiological scores for all lobes for cases with HTLV-1 for which no alternative cause of bronchiectasis was found. Each lobe was scored separately by radiologists blinded to HTLV-1 status (see Methods). The lingular segment of the left upper lobe was regarded as a separate lobe. One case (HTLV-1 PVL 242 copies per 105 PBLs) for which high-resolution computed tomography was not available for review was not included in this analysis. 10 cases with alternative causes were excluded (severe pneumonia n=5; empyema n=2; pulmonary abscess n=1; pulmonary tuberculosis n=1; severe childhood bronchiolitis n=1). #: rank-sum test; ¶: a composite score comprising those for all other radiological parameters (bronchiectasis, bronchial wall thickening, cystic bronchiectasis, saccular bronchiectasis, mucus plugging/centrilobular nodules and ground-glass opacities).