Radiological abnormality scores for cases without alternative causes of bronchiectasis according to human T-cell leukaemia virus type 1 (HTLV-1) pro-viral load (PVL)

Low PVL (<1000 copies per 105 PBLs)High PVL (≥1000 copies per 105 PBLs)p-value#
Bronchiectasis score4.53±3.677.25±3.860.039
Bronchial wall thickening3.74±3.146.17±3.010.038
Cystic bronchiectasis0.68±1.251.67±1.370.028
Saccular bronchiectasis0.50±0.991.47±1.550.025
Ground-glass opacities0.85±0.961.75±1.710.144
Mucus plugging/centrilobular nodules1.21±1.471.83±1.580.248
Total radiology abnormality score11.68±8.5620.33±9.780.022

Data are presented as n or mean±sd, unless otherwise stated. PBL: peripheral blood leukocyte. Combined radiological scores for all lobes for cases with HTLV-1 for which no alternative cause of bronchiectasis was found. Each lobe was scored separately by radiologists blinded to HTLV-1 status (see Methods). The lingular segment of the left upper lobe was regarded as a separate lobe. One case (HTLV-1 PVL 242 copies per 105 PBLs) for which high-resolution computed tomography was not available for review was not included in this analysis. 10 cases with alternative causes were excluded (severe pneumonia n=5; empyema n=2; pulmonary abscess n=1; pulmonary tuberculosis n=1; severe childhood bronchiolitis n=1). #: rank-sum test; : a composite score comprising those for all other radiological parameters (bronchiectasis, bronchial wall thickening, cystic bronchiectasis, saccular bronchiectasis, mucus plugging/centrilobular nodules and ground-glass opacities).