Descriptive, univariable and multivariate analysis of mortality among tuberculosis (TB) patients in the UK, 2001–2014
| TB patients n | Deaths n (%) | Univariable analysis OR (95% CI) | Multivariate analysis aOR (95% CI) | |
| Overall | 111 991 | 6540 (5.8) | ||
| Sex | ||||
| Male | 62 628 | 4161 (6.6) | 1.40 (1.33–1.48) | 1.37 (1.28–1.47) |
| Female | 49 146 | 2 371 (4.8) | 1.00 | 1.00 |
| Age group years | ||||
| 0–14 | 5682 | 40 (0.7) | 1.00 | 1.00 |
| 15–44 | 66 863 | 903 (1.4) | 1.93 (1.41–2.65) | 1.87 (1.29–2.71) |
| 45–64 | 22 704 | 1516 (6.7) | 10.09 (7.36–13.83) | 9.11 (6.31–13.16) |
| 65–79 | 12 094 | 2324 (19.2) | 33.55 (24.5–45.94) | 30.09 (20.84–43.44) |
| ≥80 | 4630 | 1757 (38.0) | 86.26 (62.85–118.39) | 70.80 (48.84–102.63) |
| Place of birth | ||||
| UK | 30 068 | 3062 (10.2) | 3.21 (3.04–3.39) | 1.35 (1.19–1.54) |
| Non-UK | 73 902 | 2524 (3.4) | 1.00 | 1.00 |
| Ethnic group | ||||
| White | 25 650 | 3594 (14.1) | 4.05 (3.76–4.36) | 1.17 (1.01–1.35) |
| Black African | 21 764 | 522 (2.4) | 0.61 (0.55–0.68) | 1.23 (1.07–1.41) |
| Indian | 24 276 | 940 (3.9) | 1.00 | 1.00 |
| Pakistani | 16 827 | 657 (3.9) | 1.01 (0.91–1.11) | 0.90 (0.79–1.02) |
| Bangladeshi | 3787 | 104 (2.8) | 0.70 (0.57–0.86) | 0.95 (0.74–1.22) |
| Other | 15 764 | 431 (2.7) | 0.70 (0.62–0.78) | 0.77 (0.67–0.89) |
| Site of disease | ||||
| Pulmonary sputum smear-positive | 22 526 | 1722 (7.6) | 1.00 | 1.00 |
| Pulmonary sputum smear-negative or unknown | 39 933 | 3262 (8.2) | 1.07 (1.01–1.14) | 0.91 (0.83–0.98) |
| Extrapulmonary | 49 136 | 1531 (3.1) | 0.39 (0.36–0.42) | 0.46 (0.42–0.51) |
| Previous TB diagnosis | ||||
| Yes | 7743 | 710 (9.2) | 2.03 (1.87–2.21) | 1.16 (1.05–1.28) |
| No | 88 258 | 4181 (4.7) | 1.00 | 1.00 |
| MDR-TB | ||||
| Yes | 806 | 47 (5.8) | 0.96 (0.71–1.28) | 2.40 (1.66–3.48) |
| No | 65 304 | 3975 (6.1) | 1.00 | 1.00 |
| Unknown (no culture or DSTs) | 45 881 | 2518 (5.5) | 0.90 (0.85–0.94) | 0.96 (0.89–1.03) |
aOR: adjusted OR; MDR: multidrug-resistant; DST: drug susceptibility test. Missing values: sex n=217, age n=12 661, place of birth n=8021, ethnic group n=3923, site of disease n=396, previous TB diagnosis n=15 990 and MDR-TB n=0.