TABLE 2

Descriptive, univariable and multivariate analysis including social risk factors of the number of deaths among tuberculosis (TB) patients in the UK, 2010–2014

TB patients nDeaths n (%)Univariable analysis OR (95% CI)Multivariate analysis aOR (95% CI)
Overall40 9212117 (5.2)
Sex
 Male23 5711384 (5.9)1.42 (1.29–1.55)1.29 (1.13–1.48)
 Female17 279729 (4.2)1.001.00
Age group years
 0–14179310 (0.6)1.001.00
 15–4424 439211 (0.9)1.55 (0.82–2.93)1.55 (0.62–3.84)
 45–648876522 (5.9)11.14 (5.95–20.87)10.37 (4.22–25.49)
 65–794123753 (18.3)39.84 (21.29–74.54)42.35 (17.26–103.93)
 ≥801690621 (36.8)103.58 (55.20–194.35)109.70 (44.5–270.38)
Place of birth
 UK28 799959 (8.9)2.96 (2.40–3.25)1.21 (0.96–1.53)
 Non-UK10 732923 (3.2)1.001.00
Ethnic group
 White87781086 (12.4)3.98 (3.51–4.50)1.05 (0.81–1.37)
 Black African6640128 (1.9)0.55 (0.45–0.68)0.86 (0.64–1.14)
 Indian10 263352 (3.4)1.001.00
 Pakistani6599259 (3.9)1.15 (0.98–1.35)0.91 (0.73–1.13)
 Bangladeshi151842 (2.8)0.80 (0.58–1.11)0.83 (0.52–1.33)
 Other6167155 (2.5)0.73 (0.60–0.88)0.75 (0.58–0.96)
Site of disease
 Pulmonary sputum  smear-positive13 5921142 (7.8)1.001.00
 Pulmonary sputum  smear-negative or  unknown6839441 (6.5)1.22 (1.09–1.37)0.90 (0.77–1.07)
 Extrapulmonary19 185523 (2.7)0.41 (0.36–0.46)0.47 (0.38–0.57)
Previous TB diagnosis
 Yes2689215 (8.0)2.04 (1.76–2.37)1.20 (0.98–1.47)
 No36 0401471 (4.1)1.001.00
MDR-TB
 Yes36615 (4.1)0.73 (0.43–1.23)2.47 (1.28–4.75)
 No24 3311346 (5.5)1.001.00
 Unknown (no culture  or DSTs)16 224756 (4.7)0.83 (0.76–0.91)0.96 (0.84–1.11)
Social risk factors
 ≥13207230 (7.2)1.98 (1.71–2.29)2.23 (1.83–2.71)
 030 2261135 (3.8)1.001.00

aOR: adjusted OR; MDR: multidrug-resistant; DST: drug susceptibility test.