TABLE 2

Noninvasive ventilation (NIV) characteristics and parameters

All patientsHCRF patientsHRF patientsp-value
Subjects65459460
Duration of NIV therapy# days2.74 (1.51–4.73)2.76 (1.53–1.23)2.25 (1.23–5.95)0.56
Total mask-on time h34.0 (18.0–60.0)34.0 (18.2–60.0)34.0 (10.0–60.0)0.42
Proportion of mask-on time %56.1 (41.2–69.5)55.2 (41.5–68.5)65.6 (33.7–85.2)0.07
Settings
 Inspiratory pressure cmH2O18.0 (16.0–22.0)19.0 (16.0–22.0)15.0 (12.5–16.8)<0.001
 Expiratory pressure cmH2O10 (8–14)10 (8–14)8.5 (6.5–10.0)0.07
 Pressure support cmH2O8 (5–15)8 (5–15)6 (4–11)<0.001
Out-of-protocol cessation of NIV+37 (6)29 (4)8 (13)0.02
 Intolerance of treatment20182
 Change to palliative treatment intent12750.10
 Treatment ineffective541

Data are presented as n, median (interquartile range) or n (%), unless otherwise stated. HCRF: hypercapnic respiratory failure; HRF: hypoxaemic respiratory failure. #: overall period where NIV was used (including mask-on and mask-off durations); : cumulative period where the therapy was actually in use; +: therapy was stopped before clinical stability was achieved. p-values refer to differences between HCRF and HRF cohorts.