TABLE 3

Diagnostic performance of various high-resolution computed tomography-derived measures for pulmonary hypertension defined as mean pulmonary artery (PA) pressure ≥25 mmHg on right heart catheterisation for subgroups with chronic obstructive pulmonary disease (COPD) or interstitial lung disease (ILD)

Subjects nSensitivity %Specificity %PPVNPV
COPD
 Inspiration
  MPAD ≥29 mm13688.1741.860.770.62
  PA:Ao ≥1.013650.5488.370.900.45
  MPAD and PA:Ao13650.5488.370.900.45
  MPAD or PA:Ao13688.1741.860.770.62
 Expiration
  MPAD ≥29 mm13190.1137.500.770.63
  PA:Ao ≥1.013150.5585.000.880.43
  MPAD and PA:Ao13149.4585.000.880.43
  MPAD or PA:Ao13191.2137.500.770.65
ILD
 Inspiration
  MPAD ≥29 mm23591.2437.760.670.76
  PA:Ao ≥1.023552.5580.610.790.55
  MPAD and PA:Ao23550.3684.690.820.55
  MPAD or PA:Ao23593.4333.670.660.79
 Expiration
  MPAD ≥29 mm23191.9732.980.670.74
  PA:Ao ≥1.023145.9978.720.760.50
  MPAD and PA:Ao23145.9979.790.770.50
  MPAD or PA:Ao23191.9731.910.660.73

PPV: positive predictive value; NPV: negative predictive value; MPAD: main PA diameter; PA:Ao: PA to ascending aorta ratio.