TABLE 2

Diagnostic performance of various high-resolution computed tomography (HRCT)-derived measures for pulmonary hypertension defined as mean pulmonary artery (PA) pressure ≥25 mmHg on right heart catheterisation (RHC)

Interval days#Subjects nSensitivity %Specificity %PPVNPV
Inspiration
 MPAD ≥29 mm721486.8245.880.710.70
1429586.3443.750.710.66
3042287.6043.290.710.69
6062088.0042.040.700.70
 PA:Ao ≥1.0721448.0685.880.840.52
1429549.1884.820.840.51
3042252.3382.930.830.53
6062052.8084.490.840.54
 MPAD and PA:Ao721447.2988.240.860.52
1429548.0987.500.860.51
3042251.1685.980.850.53
6062051.2087.350.860.54
 MPAD or PA:Ao721487.6043.540.700.70
1429587.4341.070.710.67
3042288.7640.240.700.69
6062089.6039.180.690.71
Expiration
 MPAD ≥29 mm720788.0039.020.690.68
1428688.7035.780.690.66
3041087.7039.240.700.67
6060088.5936.210.690.67
 PA:Ao ≥1.0720741.6079.270.750.47
1428642.9479.820.780.46
3041046.8381.650.800.49
6060048.3780.600.800.50
 MPAD and PA:Ao720741.6080.490.760.47
1428642.9480.730.780.47
3041046.0382.280.810.49
6060047.5581.470.800.49
 MPAD or PA:Ao720788.0037.800.680.67
1428688.7034.860.690.66
3041088.4938.610.700.68
6060089.4035.340.690.68

PPV: positive predictive value; NPV: negative predictive value; MPAD: main PA diameter; PA:Ao: PA to ascending aorta ratio. #: time between HRCT and RHC.