Patient characteristics
| Patients n | 20 |
| Females | 45% |
| Age years | 39±19 |
| Smoking history pack-years | 0 (0–5) |
| Daily ICS dose µg of budesonide equivalent | 800 (600–800) |
| Pre-bronchodilator FEV1 % pred | 93±20 |
| Pre-bronchodilator FVC % pred | 104±15 |
| FENO ppb | 15 (8–23) |
| Atopy# column | 45% |
| Total IgE 103 | 62 (20–217) |
| Blood eosinophils ×109 kU·L−1 | 0.13 (0.09–0.29) |
| Sputum subtype n (%) | |
| Eosinophilic | 9 (45) |
| Neutrophilic | 5 (25) |
| Sputum eosinophils | 2.6 (0.9–4.5) |
| Sputum neutrophils | 36 (17–68) |
Data are presented as mean±sd or median (interquartile range), unless otherwise stated. ICS: inhaled corticosteroid; FEV1: forced expiratory volume in 1 s; % pred: % predicted; FVC: forced vital capacity; FENO: exhaled nitrogen oxide fraction. #: defined as a positive radioallergosorbent test (RAST) for 10 standard aeroallergens.