Results from the multivariate Cox model predicting COPD mortality risk (N=783, 80 deaths#)
HR (95% CI) | p-value | |
CMV tertiles | ||
Medium | 1.65 (0.84–3.25) | 0.146 |
High | 2.30 (1.18–4.50) | 0.015 |
Chlamydophila pneumoniae tertiles | ||
Medium | 0.73 (0.37–1.42) | 0.358 |
High | 2.30 (1.28–4.10) | 0.005 |
Mycoplasma pneumoniae tertiles | ||
Medium | 0.94 (0.52–1.69) | 0.832 |
High | 0.71 (0.39–1.30) | 0.266 |
C-reactive protein in z-scores | 1.02 (0.79–1.32) | 0.881 |
Age in years | 1.11 (1.07–1.15) | <0.001 |
Sex (ref.: male) | 0.064 | |
Female | 0.57 (0.32–1.03) | |
Education level (ref.: ≥12 years) | 0.271 | |
<12 years | 1.36 (0.78–2.37) | |
BMI category (ref.: normal weight) | ||
Underweight | 6.16 (2.11–18.04) | 0.001 |
Overweight | 0.48 (0.27–0.86) | 0.014 |
Obese | 0.36 (0.12–1.10) | 0.073 |
Smoking status (ref.: never) | ||
Former | 0.86 (0.37–1.99) | 0.730 |
Current | 2.98 (1.36–6.51) | 0.006 |
Smoking history pack-years | 1.01 (1.0–1.02) | 0.073 |
FEV1 % predicted | 0.95 (0.93–0.96) | <0.001 |
Body mass index (BMI) was categorised as: underweight, <18.5 kg·m−2; normal weight, 18.5–24.9 kg·m−2; overweight, 25–29.9 kg·m−2; obese, BMI ≥30 kg·m−2. Level of education was categorised as ≤12 years or >12 years of formal education. Total numbers are lower than the 806 included participants because some individuals had missing information on covariates. HR: hazard ratio; CMV: cytomegalovirus; FEV1: forced expiratory volume in 1 s. #: includes death events with COPD listed as either the underlying cause or a coexisting condition on the death certificate.