TABLE 3

Characteristics of enrolled children undergoing hospital monitoring

CharacteristicAmoxicillinPlacebo
Overall (n=215)No treatment failure (n=199)Treatment failure (n=16)p-valueOverall (n=221)No treatment failure (n=189)Treatment failure (n=32)p-value
Age months15.4±14.815.2±14.717.4±16.40.5715.8±13.615.4±13.718.3±12.80.25
 2–11120 (55.8%)111 (55.8%)9 (56.3%)1.00114 (51.6%)103 (54.5%)11 (34.4%)0.11
 12–3567 (31.2%)62 (31.1%)5 (31.3%)80 (36.2%)64 (33.9%)16 (50.0%)
 36–5928 (13.0%)26 (13.1%)2 (12.4%)27 (12.2%)22 (11.6%)5 (15.6%)
Female108 (50.2%)105 (52.5%)3 (20.0%)0.017123 (55.7%)104 (55.0%)19 (59.4%)0.65
MUAC cm14.8±1.215.0±2.214.8±1.20.5414.6±1.214.6±1.214.6±1.00.77
 <11.50000.140001.00
 11.5–13.530 (14.0%)30 (15.1%)045 (30.4%)39 (20.6%)6 (18.8%)
 >13.5185 (86.0%)169 (84.9%)16 (100%)176 (79.6%)150 (79.4%)26 (81.2%)
Respiratory rate# breaths·min−1
 Age 2–11 months57.3±6.057.1±6.059.3±5.80.3056.8±5.756.9±5.955.9±3.60.58
  <500000.210000.64
  50–5977 (64.2%)73 (65.8%)4 (44.4%)79 (69.3%)70 (68.0%)9 (81.8%)
  60–6938 (31.7%)34 (30.6%)4 (44.4%)32 (28.1%)30 (29.1%)2 (18.2%)
  ≥705 (4.2%)4 (3.6%)1 (1.1%)3 (2.6%)3 (2.9%)0
 Age 12–59 months48.9 (7.1)49.1 (7.0)46.3 (8.4)0.3248.5 (7.1%)48.2 (7.0%)49.7 (7.4)0.37
  <400000.100000.52
  40–4955 (57.9%)49 (55.7%)6 (85.7%)64 (59.8%)53 (61.6%)11 (52.4%)
  50–5932 (33.7%)32 (36.4%)037 (34.6%)29 (33.7%)8 (38.1%)
  ≥608 (8.4%)7 (7.9%)1 (14.3%)6 (5.6%)4 (4.7%)2 (9.5%)
Oxygen saturation98 (97–99)98.5 (97–99)98 (97–99)0.2198 (97–99)98 (97–99)98 (97–99)0.89
 <90%000000
 90–93%000000
 ≥94%215 (100%)199 (100%)16 (100%)221 (100%)189 (100%)32 (100%)
Axillary temperature# °C37.9±1.038.0±1.037.7±0.90.2737.8±1.037.8±1.037.8±0.90.91
 <38100 (46.5%)89 (44.5%)11 (73.3%)0.03112 (50.7%)92 (48.7%)20 (62.5%)0.15
 ≥38115 (53.5%)111 (55.5%)4 (26.7%)109 (49.3%)97 (51.3%)12 (37.5%)
Heart rate# beats·min−1151.3±14.3151.1±14.1153.9±17.00.45150.2±13.7150.5±14.1148.7±11.20.51

Data are mean±sd, n (%) or median (interquartile range), unless otherwise stated. MUAC: mid-upper arm circumference. #: higher value between screening and enrolment visits; : lower value between screening and enrolment visits.