TABLE 2

Change in spirometry measures per 1-sd increase in skin autofluorescence (SAF) (n=4111)

Per 1-sd increase in SAF (95% CI)p-value
FEV1 LModel 1−0.06 (−0.07– −0.04)<0.001
Model 2−0.03 (−0.04– −0.02)<0.001
FVC LModel 1−0.05 (−0.07– −0.03)<0.001
Model 2−0.03 (−0.05– −0.02)<0.001
FEV1/FVCModel 1−0.005 (−0.007– −0.003)<0.001
Model 2−0.002 (−0.004– −0.000)0.120

Model 1 adjusted for age, height and sex. Model 2 adjusted for age, height, sex, weight, smoking status (never-, ex- and current smokers), pack-years, estimated glomerular filtration rate, diabetes, log(glycated haemoglobin), log(plasma glucose) and log(C-reactive protein). FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity.