Change in diffusing capacity per 1-sd increase in SAF (95% CI) | p-value | ||
DLCO mmol·min−1·kPa−1 | Model 1 | −0.16 (−0.20– −0.12) | <0.001 |
Model 2 | −0.07 (−0.11– −0.03) | <0.001 | |
DLCO/VA mmol·min−1·kPa−1·L−1 | Model 1 | −0.02 (−0.03– −0.02) | <0.001 |
Model 2 | −0.01 (−0.02–0.00) | 0.002 |
Model 1 adjusted for age, height and sex. Model 2 adjusted for age, height, sex, weight, smoking status (never-, ex- and current smokers), pack-years, estimated glomerular filtration rate, diabetes, log(glycated haemoglobin), log(plasma glucose) and log(C-reactive protein). DLCO: diffusing capacity of the lung for carbon monoxide; VA: alveolar volume.