Patients’ characteristics
| Age years | 59.5 (30–86) |
| Males/females n | 11/5 |
| Comorbidities | |
| Arterial hypertension | 11 (68.7%) |
| Type 2 diabetes mellitus | 5 (31.2%) |
| Malignancies | 2 (12.5%) |
| Pre-existing respiratory diseases | 3 (18.7%) |
| Other | 6 (37.5%) |
| Data at hospital admission | |
| Time between symptoms onset and admission days | 5 (0–15) |
| Reported symptoms | |
| Fever ≥38.0°C | 14 (87.5%) |
| Dyspnoea | 14 (87.5%) |
| Cough | 7 (43.7%) |
| Gastrointestinal symptoms | 2 (12.5%) |
| Other | 3 (18.7%) |
| Body temperature °C | 37.5 (37.2–38.9) |
| Blood gas analysis# | |
| PaO2 mmHg | 69 (48–98) |
| PaCO2 mmHg | 31 (27–38) |
| pH | 7.46 (7.39–7.52) |
| PaO2/FIO2 mmHg | 329 (228–467) |
| Laboratory findings | |
| Haemoglobin g·dL−1 | 13.8 (9.2–15.0) |
| Red blood cells ×1012 per L | 4.7 (3–0–5.4) |
| White blood cells ×109 per L | 8.6 (3.8–20.6) |
| Neutrophils ×109 per L | 7.2 (3.9–18.9) |
| Lymphocytes ×109 per L | 0.8 (0.4–2.0) |
| Monocytes ×109 per L | 0.4 (0.1–3.0) |
| Platelets ×109 per L | 231.0 (102.0–561.0) |
| C-reactive protein g·dL−1 | 13.6 (1.1–37.5) |
| Ferritin µg·L−1 | 371 (80–1364) |
| D-dimer µg·L−1 | 1256 (197–4473) |
| Respiratory support | |
| Oxygen | 12 (75.0%) |
| Positive end-expiratory pressure | 7 (43.7%) |
| High-flow nasal cannula | 1 (6.2%) |
| Noninvasive ventilation | 0 (0%) |
| Orotracheal intubation | 0 (0%) |
| Length of hospitalisation days | 25 (8–49) |
| Outcome | |
| Discharge home | 14 (87.5%) |
| Intensive care unit | 0 (0%) |
| Death | 2 (12.5%) |
| RT-PCR assays | |
| Nasopharyngeal swabs | 66 (89.2%) |
| BALF | 6 (8.1%) |
| Rectal swabs | 2 (2.7%) |
| RT-PCR repetitions during hospital stay/time from symptom onset days | |
| 3 | 16 (100%)/8 (2–20) |
| 4 | 13 (81.2%)/18 (9–27) |
| 5 | 9 (56.2%)/21 (10–27) |
| 6 | 4 (25.0%)/24 (17–24) |
| RT-PCR positive results¶ | |
| Patients | 3 (18.7%) |
| Testing | 3 (4.1%) |
| Anti-SARS-CoV-2 serum antibodies+ | |
| IgM | 8 (88.9%) |
| IgG | 9 (100%) |
| Time from symptom onset days | 25 (20–35) |
Data are presented as median (range) or n (%), unless otherwise stated. FIO2: inspiratory oxygen fraction; PaO2: arterial oxygen tension; PaCO2: arterial carbon dioxide tension; BALF: bronchoalveolar lavage fluid. #: FIO2 0.21; ¶: after two first negative results; +: N=9.