Whole lung MCC/CC and regional particle deposition indices
| MCC (Ave60) | CC (Ave60–90) | C/P | 24 h Clr | |
| Healthy adult baseline n=33 | 14.3±7.2 | 2.30±0.36 | 48±9 | |
| CB period 1 baseline n=22 | 8.4±8.2# | 2.42±1.10 | 50±16 | |
| CB HS (7% saline) | ||||
| Baseline | 9.1±6.3 | 11.7±11.5 | 2.35±0.90 | 51±15 |
| Acute | 9.6±9.7 | 10.9±10.8 | 2.23±0.66 | 51±17 |
| 2 weeks | 5.3±6.9¶ | 9.6±10.0 | 2.50±0.98 | 52±13 |
| Control (0.12% saline) | ||||
| Baseline | 9.0±10.6 | 9.4±9.9 | 2.32±1.05 | 49±15 |
| Acute | 7.7±9.4 | 8.7±9.4 | 2.35±0.94 | 51±13 |
| 2 weeks | 6.2±5.7 | 8.8±2.7 | 2.48±0.88 | 50±16 |
Data are presented as mean±sd. MCC: mucociliary clearance; CC: cough clearance; Ave60Clr: average rate of clearance through 60 min; C/P: central/peripheral; 24 h Clr: 24-h tracer clearance; CB: chronic bronchitis; HS: hypertonic saline. #: p<0.01 compared to healthy adult baseline by t-test.; ¶: p<0.05 compared to CB HS baseline.