TABLE 2

Post-bronchodilator FEV₁ and FEF_25–75 % predicted

		Baseline	Acute^#		2 weeks (sustained^¶)
		Baseline	Pre-treatment	Post-treatment	2 weeks (sustained^¶)
0.12% saline	FEV₁	57.9±12.6	59.2±12.3	57.6±13.6	59.4±13.3
0.12% saline	FEF_25–75	31.6±13.7	33.2±13.0	31.7±13.6	34.5±16.2
7% saline	FEV₁	58.9±13.2	58.0±12.6	58.0±12.5	59.2±12.9
7% saline	FEF_25–75	33.6±14.9	34.6±17.5	31.6±16.5	33.5±15.1

Data are presented as mean±sd. FEV₁: forced expiratory volume in 1 s; FEF_25–75: forced expiratory flow at 25–75% of forced vital capacity. ^#: acute values were measured immediately before and 2 h after first dose of study treatment; ^¶: sustained values measured ∼12 h after final dose of 2-week treatment period.