Lung function data

FEV1 % pred99.1±9.2*89.2±16.699.0±12.383.0±13.60.02
FVC % pred104.3±5.4*98.5±14.7*96.9±11.9*80.9±9.8<0.001
FEV1/FVC %77.0±5.776.7±8.582.0±6.983.1±4.20.051
ERV % pred62.5±39.869.1±29.744.3±35.451.4±46.50.53
TLC % pred103.4±8.72*98.2±14.096.1±12.887.4±8.90.02
RV % pred132.4±39.4*129.1±36.5*99.5±30.482.7±36.9<0.01
RV/TLC % pred128.3±30.2136.3±42.5*102.5±26.893.9±35.50.02
FRC % pred96.0±22.8+98.6±10.0+76.2±11.973.9±16.6<0.001
sGaw % pred119±92.0127.9±72.6107.8±78.1156.6±92.90.59
PC20 mg·mL−1 methacholine50 (22.2–64)2.8 (0.1–12.8)64 (64–64)1.4(0.03,16)<0.0001

Data are presented as mean±sd or median (range), unless otherwise stated. Predicted values for spirometry are based on NHANES III [21], and those for lung volumes are based on Goldman and Becklake [22]. FEV1: forced expiratory volume in 1 s; % pred: % predicted; FVC: forced vital capacity; ERV: expiratory reserve volume; TLC: total lung capacity; RV: residual volume; FRC: functional residual capacity; sGaw: specific airway conductance; PC20: provocative concentration causing a 20% fall in FEV1. #: p-value shown for one-way analysis of variance for normally distributed variables, and Kruskal–Wallis test for non-parametric variables; *: p<0.05 compared with Obese Asthma group, post hoc comparison with Bonferroni correction; : p<0.05 compared with asthma groups, post hoc comparison with Bonferroni correction; +: p<0.05 compared with obese groups, post hoc comparison with Bonferroni correction.