EPT group (n=11) | p-value | IPT group (n=10) | p-value | |||
Pretreatment | After 12 weeks | Pretreatment | After 12 weeks | |||
Body weight kg | 57.2±9.8 | 57.3±10.1 | 0.9425 | 55.2±10.1 | 55.4±10.2 | 0.1354 |
Total lean mass kg | 41.9±6.5 | 41.9±6.5 | 0.4648 | 41.2±4.8 | 37.5±13.6 | 0.0742 |
Total fat mass kg | 12.0±4.6 | 12.3±5.1 | 0.3203 | 12.1±6.1 | 11.7±6.1 | 0.5703 |
MEP cmH2O | 125.4±24.7 | 153.4±32.4** | 0.0047 | 114.9±45.4 | 117.9±47.1 | 0.5943 |
MIP cmH2O | 77.9±19.3 | 85.9±21.8 | 0.1530 | 67.9±17.2 | 78.0±19.0* | 0.0217 |
PFT | ||||||
FEV1 L | 0.87±0.19 | 0.89±0.19 | 0.3516 | 1.18±0.40 | 1.15±0.41 | 0.1563 |
FEV1/FVC % | 33.9±6.0 | 33.4±4.1 | 0.9648 | 38.9±6.5 | 40.0±9.0 | 0.4316 |
%FEV1 % | 32.8±7.0 | 33.8±6.9 | 0.2500 | 45.1±14.2 | 44.0±14.9 | 0.1602 |
VC L | 2.75±0.56 | 2.83±0.60 | 0.1758 | 3.14±0.80 | 2.98±0.91 | 0.0605 |
%VC % | 84.8±12.3 | 87.8±13.2 | 0.1230 | 98.0±22.8 | 92.9±26.5 | 0.0645 |
IC L | 1.72±0.21 | 1.83±0.38 | 0.1221 | 2.06±0.52 | 1.99±0.59 | 0.5566 |
SGRQ symptoms domain | 47.4±21.7 | 43.5±21.0 | 0.7344 | 53.8±22.8 | 56.7±20.2 | 0.7344 |
SGRQ activity domain | 66.9±19.1 | 59.6±19.3 | 0.0156 | 56.1±28.5 | 56.3±26.5 | 1.0000 |
SGRQ impacts domain | 34.6±18.2 | 24.5±18.7 | 0.0049 | 25.7±15.9 | 28.0±21.2 | 0.7695 |
SGRQ total score | 46.7±17.2 | 38.7±18.3 | 0.0137 | 38.8±19.8 | 41.2±21.8 | 1.0000 |
Data are presented as mean±sd. EPT: expiratory pressure load training; IPT: inspiratory pressure load training; MEP: maximal expiratory pressure; MIP: maximal inspiratory pressure; PFT: pulmonary function test; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; VC: vital capacity; IC: inspiratory capacity; SGRQ: St. George's Respiratory Questionnaire. *: p<0.05; **: p<0.01, by the least squares means Tukey's honestly significant difference, compared with the pretreatment.