TABLE 3

High-resolution computed tomography (HRCT) findings, timing, ground-glass opacities (GGO) and correlation to pathologic findings in both groups

No AE-IPFAE-IPF
Subjects5237
Baseline HRCT UIP pattern (typical/probable/indeterminate)33/14/525/9/3
GGO in chest HRCT at any time before lung transplantation17/52 (33)19/37 (51)
GGO severity in chest HRCT at any time scored by thoracic radiologist (mild/moderate/severe#)5/2/103/0/16
Had chest HRCT 30 days prior to lung transplantation2/52 (4)13/28 (46)
Had GGO in chest HRCT 30 days prior to lung transplantation1/2 (50)9/13 (69)
Had GGO in chest HRCT 30 days prior to lung transplantation and acute pathological process in explant lung0/19/9 (100)

Data are presented as n or n (%). AE-IPF: acute exacerbation of idiopathic pulmonary fibrosis; UIP: usual interstitial pneumonia. #: mild: focal/patchy involvement, moderate: neither mild nor severe, severe: bilateral extensive; : nine out of 37 patients died before receiving lung transplantation.