Gaps in the COVID-19 research agenda informed by lessons learned from tuberculosis (TB)
| Challenges shared by TB and COVID-19 | Potential solutions informed by lessons learned from TB |
| Need for community-based strategies | Research on interventions such as social distancing and mask use |
| Implementation of rapid diagnostic tests | Integrated use of test platforms such as Gene Xpert |
| Interpretation of diagnostic tests | Clear communication regarding test sensitivity and interpretation of negative predictive value (for molecular tests) and positive predictive value (for serological tests) |
| Slow drug development, including testing in combination with other drugs | Use of adaptive trial designs |
| Inequitable access to new drugs | Principles of equity should be explicitly used to guide drug distribution |
| Vaccine hesitancy | Outreach to affected communities, cultural adaptation of communication strategies |