Treatment difference in COPD assessment test (CAT) score at 90 days for different definitions of adherence

Usage definitionsActive usersAdjusted treatment estimate95% confidence interval
Total usageActivated app18−1.63−5.56–2.30
>30 days12−2.47−8.46–3.53
≥60 days7−4.28−15.00–6.43
Sustained usage50% weeks active14−2.13−7.24–2.98
75% weeks active12−2.47−8.46–3.53
90% first, 90% second10−2.93−9.97–4.10

Analysis only includes the 54 participants who were at the final study visit. All participants in usual care are assumed not to have used the app under all usage definitions.