Success rates of MBW investigations in awake preschool children
| Cohort | Centres | Number of performed investigations n | Number of performed measurements mean±sd | Number of successful measurements mean±sd | At least 1 successful measurement n (%) | At least 2 successful measurements n (%) |
| All | Experienced | 62 | 3.8±1.6** | 2.1±0.8 | 58 (93.5) | 54 (87.1) |
| Unexperienced | 29 | 5.2±2.5 | 2.1±1.3 | 24 (82.8) | 21 (72.4) | |
| Controls | Experienced | 11 | 4.2±2.1 | 2.1±0.5* | 11 (100.0) | 10 (90.9) |
| Unexperienced | 4 | 5.5±1.9 | 3.0±0.8 | 4 (100.0) | 4 (100.0) | |
| CF | Experienced | 40 | 3.7±1.7* | 1.9±0.9 | 36 (90.0) | 33 (82.5) |
| Unexperienced | 23 | 5.3±2.6 | 2.0±1.2 | 19 (82.6) | 16 (69.6) | |
| Other lung diseases | Experienced+ | 11 | 3.8±0.8 | 2.7±0.5 | 11 (100.0) | 11 (100.0) |
| Unexperienced§ | 2 | 3.0±1.4 | 1.5±2.1 | 1 (50.0) | 1 (50.0) |
Experienced centres are the CF Center at Airway Research Center North, the CF Center at Biomedical Research in Endstage and Obstructive Lung Disease Hannover, and the CF Center at Translational Lung Research Center Heidelberg. Unexperienced centres are the CF Center at Universities of Giessen and Marburg Lung Center and the CF Center at Charité - Universitätsmedizin Berlin. MBW: multiple-breath washout; CF: cystic fibrosis. *: p<0.05 and **: p<0.01 versus unexperienced centres; +: limited to the CF Center at Airway Research Center North and the CF Center at Translational Lung Research Center Heidelberg; §: limited to the CF Center at Charité - Universitätsmedizin Berlin.