Results of all regression analysis and 90-day estimates for primary and secondary outcomes
| Effectiveness outcomes | 90-day change from baseline | Regression sample size | Adjusted group difference | 95% confidence interval | p-value | |
| myCOPD# | Usual care¶ | |||||
| Primary outcomes | ||||||
| CAT score | −1.8 (5.76) | 0.0 (5.54) | 58 | MD: −1.27 | −4.47–1.92 | 0.435 |
| ≥1 inhaler error | −0.3 (0.70) | 0.1 (0.71) | 54 | OR: 0.30 | 0.09–1.06 | 0.061 |
| Average inhaler errors | −0.3 (1.61) | −0.1 (1.20) | 54 | IRR: 0.97 | 0.52–1.81 | 0.928 |
| Secondary outcomes | ||||||
| PAM score | −0.7 (14.28) | −3.5 (13.07) | 58 | MD: −0.98 | −8.22–6.26 | |
| PAM level | 0.1 (0.83) | −0.3 (0.70) | 54 | OR: 1.65 | 0.46–5.85 | |
| SEAMS | 1.0 (0.00) | 0.0 (−3.00) | 58 | MD: 0.33 | −2.22–2.87 | |
| EQ5D score | 0.1 (0.23) | 0.0 (0.18) | 54 | MD: −0.04 | −0.12–0.05 | |
| EQ5D VAS | 62.0 (21.35) | 60.9 (19.92) | 53 | MD: 0.86 | −9.46–11.18 | |
| Exacerbations | 0.2 (1.28) | 0.2 (0.72) | 60 | IRR: 2.55 | 1.17–5.54 | |
| Activity level (mean daily steps) | 226.8 (5680.38) | 11 915.9 (37 447.87) | 13 | MD: −2252.94 | −10 433.77–5927.88 | |
| Smoking | −0.0 (0.20) | −0.0 (0.33) | 53 | OR: 0.76 | 0.07–7.89 | |
| Cessation | 2 (6.9) | 3 (9.7) | 16 | OR: 0.60 | 0.04–9.09 | |
All regression models included adjustment for baseline values, COPD severity and centre. n in 90-day observed outcome is defined as participants who were at the final study visit. CAT: COPD assessment test; MD: mean difference; OR: odds ratio; IRR: incidence rate ratio; PAM: patient activation measurement; SEAMS: self-efficacy for appropriate medication use scale; EQ5D: EuroQol 5 dimensions; EQ5D VAS: EuroQol 5 dimensions visual analogue scale. #: n=24; ¶: n=30. Example interpretation: MD – A difference of −1.27 means after adjustment for baseline values, COPD severity and centre the mean CAT score was 1.27 lower in myCOPD. IRR – A difference of 0.97 means after adjustment for baseline values, COPD severity and centre the rate of average inhaler errors for myCOPD was 0.97 times the rate of average inhaler errors for usual care. OR – A difference of 0.30 means after adjustment, the odds of ≥1 inhaler error in myCOPD were 0.30 times the odds of ≥1 inhaler error in usual care.