TABLE 1

Characteristics of patients with cancer and sarcoidosis

Female n (%)72 (54.2)
Age at time of sarcoid-like granuloma diagnosis years mean/median64.5/65
Underlying cancer n (%)
 Skin cancer30 (22.5)
 Breast cancer27 (20.3)
 Lymph cancer17 (12.7)
 Prostate cancer14 (10.5)
 Lung cancer12 (9)
 Colon cancer9 (6.7)
 Urinary bladder cancer8(6.0)
 Cervical cancer7 (5.3)
 Head and neck cancer6 (4.5)
 Sarcoma5 (3.8)
 Kidney cancer5 (3.8)
 Pancreatic cancer4 (3.0)
 Conjunctival cancer1 (0.7)
Cancer treatment before diagnosis of sarcoidosis n (%)
 Surgery91 (68.4)
 Chemotherapy54 (40.6)
 Radiation38 (28.6)
Chemotherapy agents before diagnosis of sarcoidosis n (%)
 Doxorubicin15 (11.3)
 Cisplatin11 (8.2)
 Cyclophosphamide11 (8.2)
 Gemcitabine9 (6.7)
 5-Fluorouracil9 (6.7)
 Carboplatin9 (6.7)
 Rituximab9 (6.7)
MAB treatment before cancer diagnosis n (%)
 Anti-CD209 (6.7)
 PD-1 immune checkpoint4 (3)
 Anti-Her2neu2 (1.5)
 Anti-CTLA42 (1.5)
 Anti-VEGF1 (0.75)
Cancer stage at time of sarcoid-like granuloma diagnosis
 Stage 124 (15.8)
 Stage 217 (12)
 Stage 318 (12.7)
 Stage 412 (7.5)
Interval between cancer and sarcoid-like granulomas n(%)
 <1 year24 (18.9)
 1–5 years54 (42.5)
 >5 years49 (38.5)
Most common symptom at time of sarcoidosis diagnosis n (%)
 Dyspnoea20 (15)
 Cough18 (13.5)
 Fatigue16 (12)
Smoking n (%)
 Current7 (5.2)
 Past48 (36.1)
 Never smoker76 (57.1)
 Mean number of years of smoking28.5
Sarcoidosis stage at the time of diagnosis n (%)
 Stage 151 (38.3)
 Stage 273 (54.9)
 Stage 35 (3.7)
 Stage 42 (1.5)