TABLE 2

Comparison of diagnostic findings at baseline and 6-month (balloon pulmonary angioplasty (BPA)) or 12-month (pulmonary endarterectomy (PEA)) follow-up

ParameterBaseline6-MFU/12-MFUp-value (total)
TotalPEABPATotalPEABPA
WHO-FC n
 I000693039
 II14140452223
 III783147936
 IV331023202
RAP mmHg7 (5–9)7 (5–9)7 (5–9)5 (4–7)5 (4–7)5 (4–7)<0.001
PCWP mmHg9 (8–12)9(8–13)9 (8–11)9 (7–11)9 (7–12)/9 (8–11)0.175
Mean PAP mmHg42 (36–49)44(36–50)40 (36–49)25 (20–33)20 (17–24)30 (25–35)<0.001
Mean PAP reduction %35 (21–53)53 (36–63)10 (6–16)
PVR Wood units6.8 (5.3–9.6)7.1 (5.2–11.9)6.8 (5.2–8.6)3.4 (2.4–4.9)2.5 (1.8–3.5)3.9 (3.0–5.3)<0.001
PVR reduction %46 (25–63)63 (40–81)40 (23–54)
CI L·min−1·m−22.4 (2.1–2.8)2.3 (1.9–2.6)2.6 (2.1–3.0)2.6 (2.3–2.9)2.4 (2.3–2.8)2.7 (2.4–3.0)0.009
6MWD m405±99409±145410±101445±113438±129449±106<0.001
LVEF %55 (55–60)55 (55–60)55 (55–60)55 (55–60)55 (55–58)55 (55–60)0.21
TAPSE mm19±519±619±519±517±421±40.90

Data are presented as n, mean±sd or median (interquartile range), unless otherwise stated. 6-/12-MFU: 6-/12-month follow-up; WHO: World Health Organization; FC: functional class; RAP: right atrial pressure; PCWP: pulmonary capillary wedge pressure; PAP: pulmonary arterial pressure; PVR: pulmonary vascular resistance; CI: cardiac index; 6MWD: 6-min walk distance; LVEF: left ventricular ejection fraction; TAPSE: tricuspid annular plane systolic excursion.