TABLE 3

Comparison of biomarker findings at baseline and 6-month (balloon pulmonary angioplasty (BPA)) or 12-month (pulmonary endarterectomy (PEA)) follow-up

ParameterBaseline6-MFU/12-MFUp-value (total)
TotalPEABPATotalPEABPA
MR-proANP pmol·L−1156 (91–246)170 (97–243)145 (86–246)99 (58–145)98 (57–160)101 (59–142)<0.001
Copeptin pmol·L−17.7 (4.6–14.2)8.0 (4.4–14.7)7.1 (4.6–13.5)6.3 (3.7–12.6)6.2 (3.8–13.7)6.4 (3.7–12.2)0.009
NT-proBNP ng·L−1845 (178–1875)1094 (136–2163)744 (195–1564)142 (72–335)192 (98–408)121 (67–243)<0.001
Creatinine µmol·L−186±2888±3184±0.3080±2681±3178±21<0.001
eGFR mL·min−1·m−282.5±25.781.1±24.783.6±26.691.7±37.792.0±27.191.5±44.5<0.001
eGFR ≤60 mL·min−1·m−221 (16.8)12 (9.6)

Data are presented as median (interquartile range), mean ±sd or n (%), unless otherwise stated. 6-/12-MFU: 6-/12-month follow-up; MR-proANP: mid-regional pro-atrial natriuretic peptide; NT-proBNP: N-terminal pro-B-type natriuretic peptide; eGFR: estimated glomerular filtration rate.