Examined treatable traits, measurement instruments, cut-off values applied and appropriate evidence-based nonpharmacological interventions
Treatable trait | Measurement instrument | Cut-off value | Possible (combinations of) intervention(s) | |
1 | Current smoking | Medical history | Positive on history | Simple advice, combination of behavioural treatment and pharmacotherapy [17] |
2 | Activity-related dyspnoea [18] | Medical Research Council dyspnoea scale | Grade ≥3 | exercise training, pulmonary rehabilitation [19] |
3 | Frequent exacerbations [13] | Medical history | ≥2 exacerbations or ≥1 hospitalisation past year | Exacerbation action plan [20], pulmonary rehabilitation [19] |
4 | Poor nutritional status [21] | BMI | BMI<21 or BMI>30 kg·m−2 | Nutritional support [22], dietary counselling and calorie restriction plus resistance exercise training [23] |
5 | Severe fatigue [24] | Checklist individual strength-fatigue | ≥36 points | Pulmonary rehabilitation [19] |
6 | Depressed mood [25] | Beck depression inventory | ≥4 points | Cognitive behavioural therapy [26], pulmonary rehabilitation [19] |
7 | Poor exercise capacity [27] | Six-minute walk test | <70% predicted | Exercise training, pulmonary rehabilitation [19] |
8 | Low habitual physical activity [27] | Move monitor | <5000 steps·day−1 | Exercise training plus physical activity counselling [28] |
9 | Patient activation for self-management [29] | Patient activation measure | Level 1–2 | Self-management program [30] |