Clinical response to bronchial thermoplasty
Parameter | Baseline | 6 months post-procedure | 12 months post-procedure | p-value |
ACQ score | 3.4±1.0 | 1.8±0.9 | 1.5±0.9 | 0.001 |
FEV1 % pred | 42.9±11.5 | 46.8±5.8 | 48.2±13.3 | 0.350 |
SABA puffs per day | 11.0 (18.5) | 3.25 (7.75) | 2.5 (6.25) | 0.080 |
OCS mg·day−1 | 5.0 (6.75) | 0 (3.75) | 0 (6.25) | 0.005 |
Exacerbations per 6 months | 2.0 (2) | 0 (1.25) | 0 (1.0) | 0.008 |
Data are presented as mean±sd or median (interquartile range), unless otherwise stated. ACQ: Asthma Control Questionnaire; FEV1: forced expiratory volume in 1 s; SABA: short-acting β-agonist; OCS: oral corticosteroid (prednisolone). p: analysis of variance or Friedman's test. All p-values are significant between baseline and 6 months and not thereafter.