TABLE 1

Prevalence of pulmonary fibrosis (PF) in decedents with and without diabetes mellitus (DM)

VariableDecedents without DM#Decedents with DMOR+ (95% CI)
Total deathsPF presentTotal deaths with PF %PF mortality rate % change 2007–2017p-value for trendTotal deathsPF presentTotal deaths with PF %PF mortality rate % change 2007–2017p-value for trend
Sex
 Female12 136 43386 1190.71−4.50.071 243 50970220.56−14.0−0.010.79 (0.78–0.81)
 Male11 551 233104 3160.90+6.00.031 374 39399640.720.80 (0.78–0.82)
Age years
 45–541 803 88548790.27−17.30.001172 6213740.220.80 (0.72–0.89)
 55–643 221 87716 1580.50−16.7<0.001411 61616450.40−17.80.030.80 (0.76–0.84)
 65–744 296 69640 4230.95−13.7<0.001614 37843520.71−24.6<0.0010.75 (0.73–0.78)
 75–846 221 18069 3751.12−2.170.002766 85164430.84−6.30.0010.75 (0.73–0.77)
 ≥858 144 02859 6000.73+3.40.03652 43641720.640.87 (0.85–0.90)
Race
 Native-American118 03614331.21+24.1<0.00124 5132070.840.69 (0.60–0.80)
 Asian490 44344070.9075 8625180.680.76 (0.69–0.83)
 Black2 466 55087950.36−8.00.01382 78912130.32−17.80.0030.89 (0.84–0.94)
 White19 327 231161 2170.83+5.10.061 895 44413 1320.690.83 (0.81–0.84)
 Hispanic1 223 99114 2791.17231 95418830.810.69 (0.66–0.73)
UCD
 PF132 32298070.60 (0.58–0.62)
 Ischaemic heart disease9153−27.70.00214861.90 (1.79–2.01)
 Lung cancer49303910.89 (0.80–0.98)
 Pneumonia1737970.62 (0.51–0.77)
 Heart failure13801180.96 (0.79–1.16)
 Cerebrovascular disease12411521.38 (1.16–1.63)
 Pulmonary heart875770.99 (0.78–1.25)
  disease
 Other38 79748581.57 (1.51–1.62)

International Classification of Diseases, 10th revision, codes used for underlying cause of death (UCD) are as follows. Pulmonary fibrosis: J84.1; ischaemic heart disease: I20–I25; lung cancer: C34–C34.9; pneumonia: J09–J18.9; heart failure: I50–I50.9; cerebrovascular disease: I60–I69.8; pulmonary heart disease: I26–I27.9. If no data are shown for % change in rate, the regression analysis of the data did not indicate a significant change in trend during the time period. #: n=23 687 666; : n=2 617 902; +: the overall risk of PF in diabetics compared to nondiabetics.