TABLE 3

The most prevalent diagnoses among patients with a diagnosis of idiopathic pulmonary fibrosis (IPF) established within 3 years prior to the IPF diagnosis and a randomly assigned index date among controls

DiagnosisICD-10IPF casesControls
n (%)First occurrence relative to IPF diagnosis months median (IQR)n (%)First occurrence relative to index date months median (IQR)
Interstitial pulmonary diseases other than J84.1AJ84298 (45.8)2.3 (1.0–3.9)n<10n<10
Abnormalities of breathingR0693 (14.3)2.2 (0.9–3.7)32 (0.5)3.6 (2.2–4.4)
Respiratory failure, not elsewhere classifiedJ9658 (8.9)2.3 (0.9–4.5)18 (0.3)3.8 (1.9–5.0)
Pneumonia, organism unspecifiedJ1851 (7.8)2.2 (0.9–4.1)32 (0.5)3.2 (2.0–4.8)
Abnormal findings on diagnostic imaging of lungR9139 (6.0)2.2 (1.1–4.0)n<10n<10
Atrial fibrillation and flutterI4837 (5.7)1.9 (1.2–3.8)69 (1.1)3.1 (1.7–4.8)
Other COPDJ4433 (5.1)1.8 (0.5–3.0)47 (0.7)3.2 (1.7–4.3)
Bacterial pneumonia, not elsewhere classifiedJ1524 (3.7)2.6 (1.2–3.9)22 (0.3)2.8 (1.2–3.4)
Heart failureI5023 (3.5)1.6 (0.5–4.7)44 (0.7)2.7 (1.4–4.4)
CoughR0520 (3.1)2.8 (1.8–3.9)n<10n<10
Other pulmonary heart diseasesI2719 (2.9)1.9 (1.0–4.2)n<10n<10
Chronic ischaemic heart diseaseI2518 (2.8)2.2 (0.5–3.4)46 (0.7)3.0 (1.8–4.2)
Osteoporosis without pathological fractureM8117 (2.6)2.5 (1.6–4.1)22 (0.3)2.5 (1.4–3.8)
Non-insulin-dependent diabetes mellitusE1116 (2.5)3.1 (1.8–4.4)46 (0.7)3.3 (1.9–4.6)
Nonrheumatic aortic valve disordersI3515 (2.3)2.5 (2.1–3.2)26 (0.4)3.2 (1.6–4.2)
Essential (primary) hypertensionI1015 (2.3)2.7 (0.5–4.0)73 (1.1)3.1 (1.9–4.3)
Angina pectorisI2015 (2.3)2.8 (2.3–4.7)23 (0.4)3.1 (2.0–4.7)
Senile cataractH2514 (2.2)3.9 (1.5–4.2)61 (0.9)2.9 (1.3–4.4)
Other respiratory disordersJ9813 (2.0)1.7 (0.7–3.6)n<10n<10
Haemorrhage from respiratory passagesR0413 (2.0)2.6 (0.3–4.2)11 (0.2)3.2 (2.1–4.0)
Complications and ill-defined descriptions of heart diseaseI5112 (1.8)2.0 (0.0–4.6)n<10n<10
Malaise and fatigueR5312 (1.8)2.3 (0.6–3.4)22 (0.3)2.2 (1.1–3.2)
Malignant neoplasm of bronchus and lungC3410 (1.5)2.9 (1.7–4.2)18 (0.3)2.3 (0.8–4.6)

ICD-10: International Classification of Diseases, 10th revision; IQR: interquartile range.