TABLE 1

Comparison of the analytical subsample (n=888) with the whole Isle of Wight (IOW) cohort (n=1261) with regard to age of onset of pubertal event, lung function and height

Variables	Cohort samples	Subsamples	p-value
Subjects n	1261	888
Age of pubertal events years
Female
Breast growth	12.43±1.58	12.45±1.58	0.87
Body hair growth	12.25±1.43	12.26±1.41	0.91
Growth spurt	12.52±1.70	12.54±1.70	0.90
Skin changes	13.11±1.50	13.06±1.50	0.55
Menarche	12.72±1.42	12.72±1.37	0.95
Male
Body hair growth	13.41±1.37	13.28±1.34	0.10
Growth spurt	13.72±1.67	13.58±1.64	0.14
Voice deepening	14.24±1.24	14.14±1.21	0.14
Facial hair growth	15.38±1.16	15.28±1.15	0.11
Skin changes	13.99±1.38	13.97±1.36	0.81
Lung function age 26 years L
Female
FVC	4.24±0.54	4.27±0.54	0.32
FEV₁	3.42±0.43	3.44±0.42	0.49
Male
FVC	5.85±0.82	5.88±0.81	0.58
FEV₁	4.61±0.72	4.63±0.71	0.67
Height cm
Female
Age 10	139.10±6.47	139.10±6.40	0.92
Age 18	164.70±6.33	164.80±6.17	0.78
Male
Age 10	139.00±5.89	139.10±5.84	0.74
Age 18	178.20±6.87	177.90±6.63	0.42

Data are presented as mean±sd unless otherwise stated. FVC: forced vital capacity; FEV₁: forced expiratory volume in 1 s.