Baseline characteristics on first day of mechanical ventilation and outcomes in patients with acute respiratory distress syndrome (ARDS) secondary to novel coronavirus disease (COVID-19) and ARDS from other diseases
| Variables | CoV-ARDS | noCoV-ARDS | p-value |
| Subjects n | 169 | 163 | |
| Age years | 66 (59–71) | 72 (62–78) | <0.001 |
| Male sex | 133 (78.7) | 106 (65.4) | 0.007 |
| Body mass index kg·m−2 | 28 (25–31) | 27 (24–31) | 0.02 |
| Diabetes mellitus | 26 (15.4) | 47 (29) | 0.003 |
| Arterial hypertension | 90 (53.3) | 96 (59.3) | 0.27 |
| COPD | 4 (2.4) | 22 (13.5) | <0.001 |
| Positive end-expiratory pressure cmH2O | 12 (10–14) | 8 (5–9) | <0.001 |
| Peak airway pressure cmH2O | 30±5 | 22±6 | <0.001 |
| Plateau airway pressure cmH2O | 23±4 | 19±3 | <0.001 |
| pH | 7·29±0.12 | 7·33±0.14 | 0.15 |
| PaCO2 mmHg | 56±16 | 46±12 | <0.001 |
| Compliance of the respiratory system mL·cmH2O−1 | 28 (22–34) | 35 (25–43) | <0.001 |
| Minute ventilation L·min−1 | 8.8±1.3 | 8.7±2.3 | 0.62 |
| Corrected minute ventilation L·min−1 | 12.4 (9.3–15) | 9.6 (7.5–11.8) | <0.001 |
| PaO2/FIO2 mmHg | 111 (86–153) | 140 (100–198) | <0.001 |
| Tidal volume/ideal body weight mL·kg−1 | 5.9±0.8 | 6.6±1.3 | <0.001 |
| Length of stay in intensive care unit | 10 (5–18) | 7 (3–20) | 0.22 |
| Length of stay in hospital | 15 (9–24) | 20 (11–33) | 0.002 |
| In-hospital mortality | 86 (50.9) | 43 (26.6) | <0.001 |
| Pneumomediastinum/subcutaneous emphysema | 23 (13.6) | 3 (1.9) | <0.001 |
Data are presented as median (interquartile range), n (%) or mean±sd, unless otherwise stated. CoV-ARDS: ARDS from COVID-19; noCoV-ARDS: ARDS secondary to other diseases; PaCO2: arterial carbon dioxide tension; PaO2: arterial oxygen tension; FIO2: inspiratory oxygen fraction.