TABLE 2

Patient characteristics according to the level of disease on computed tomography pulmonary angiography

Level 1Level 2Level 3Level 4p-value
Patients2054233
Female9 (45)23 (43)19 (83)1 (33)0.01
Age years60±1657±1359±1742±160.2
Functional class2.8±0.82.7±0.73.0±0.53.0±0.00.3
6MWD m319±147420±161327±114475±990.01
BNP pg·mL−1460±508190±299243±38349±660.04
Mean PAP mmHg48±1541±1245±1233±130.08
Systolic PAP mmHg79±2168±2074±2355±220.1
Diastolic PAP mmHg30±1225±826±820±90.1
RAP mmHg11±610±411±55±20.2
PCWP mmHg12±312±410±47±20.03
Cardiac index L·min·m−21.8±0.52.1±0.52.4±0.72.5±0.30.001
PVR dyn·s·cm−51029±556611±335731±387458±2410.001
Pre-operative echo RV size0.9
 Normal21151
 Mild21041
 Moderate51450
 Severe91581
Pre-operative echo RV function0.7
 Normal41851
 Mild3920
 Moderate615112
 Severe4740
Pre-operative PH therapy3 (15)9 (17)9 (39)2 (67)0.04

Data are presented as n, n (%) or mean±sd, unless otherwise stated. 6MWD: 6-min walk distance; BNP: brain natriuretic peptide; PAP: pulmonary arterial pressure; RAP: right atrial pressure; PCWP: pulmonary capillary wedge pressure; CI: cardiac index; PVR: pulmonary vascular resistance; echo: echocardiogram; RV: right ventricular; PH: pulmonary hypertension.