TABLE 2

Combined pulmonary fibrosis and emphysema (CPFE) lung cancer characteristics

Histology
 NSCLC/small cell carcinoma23/3 (88/12)
 Adenocarcinoma8 (35)
 Squamous cell13 (57)
 Large cell1 (4)
 Other1 (4)
Clinical staging
 NSCLC
  Stage I5 (21.7)
  Stage II5 (17.4)
  Stage IIIA3 (17.4)
  Stage IIIB1 (4.3)
  Stage IV9 (39)
 Small cell lung cancer
  Limited disease3 (100)
Location
 Left/right12/11 (52/48)
 Left lower lobe8 (31)
 Right lower lobe8 (31)
 Left upper lobe3 (12)
 Right upper lobe3 (12)
 Other (right middle lobe, lingula, hilar only)4 (15)
 Located within 2 cm of pleural edge16 (64)
Treatment
 No therapy (direct hospice or palliation)4 (15)
 Chemotherapy alone1 (4)
 Radiation alone (including SBRT)7 (27)
 Chemotherapy and radiation6 (23)
 Surgical resection alone6 (23)
 Surgical resection+chemotherapy or radiation2 (8)
Deaths21 (81)
Cause of death
 Primary cancer12 (55)
 Infection3 (15)
 Acute exacerbation of ILD1 (5)
 Unrelated to CPFE and/or lung cancer2 (10)
 Unknown3 (15)

Data are presented as n (%). n=26. NSCLC: nonsmall cell lung cancer; SBRT: stereotactic body radiotherapy; ILD: interstitial lung disease.