TABLE 4

Univariable Cox regression predictors of death in combined pulmonary fibrosis and emphysema (CPFE)-lung cancer patients

Univariable HR (95% CI)p-value
Age at cancer diagnosis years1.03 (0.96–1.09)0.43
Male sex %0.91 (0.35–2.61)0.53
Smoking pack-years1.01 (0.98–1.02)0.51
Finger clubbing1.15 (0.40–2.86)0.78
Home oxygen use1.32 (0.52–3.57)0.56
RVSP mmHg1.03 (0.99–23.97)0.05
FVC % pred0.98 (0.95–1.01)0.16
FEV1 % pred0.99 (0.97–1.02)0.39
DLCO % pred0.97 (0.93–1.00)0.14
Presence of honeycombing3.03 (1.16–7.91)0.02
Adenocarcinoma versus others1.95 (0.72–4.81)0.17
Stage at presentation (late or nonresectable (stage III and IV, with small cell) versus potentially resectable NSCLC (stages I and II))4.77 (1.8–14.94)0.001
Surgical resection performed0.29 (0.09–0.87)0.02

n=26. Bold type represents statistical significance. HR: hazard ratio; RVSP: right ventricular systolic pressure; FVC: forced vital capacity; FEV1: forced expiratory volume in 1 s; DLCO: diffusing capacity of the lung for carbon monoxide; NSCLC: nonsmall cell lung cancer.