TABLE 2

Odds ratios of maternal asthma exacerbations on adverse perinatal outcomes

No exacerbationExacerbationOR (95% CI)aOR# (95% CI)
Subjects n32 3991430
Birthweight categories
 ≤2499 g1180 (3.6)60 (4.2)1.21 (0.92–1.59)1.02 (0.75–1.39)
 2500–2999 g3601 (11.1)224 (15.7)1.48 (1.27–1.72)1.45 (1.24–1.70)
 3000–3999 g21 595 (66.7)909 (63.7)Ref.Ref.
 ≥4000 g5965 (18.4)235 (16.5)0.94 (0.81–1.09)0.94 (0.80–1.10)
 Missing58 (0.2)2 (0.1)
Preterm birth
 Yes1834 (5.7)85 (5.9)1.05 (0.84–1.32)1.00 (0.79–1.28)
 Missing13 (0.04)2 (0.1)
Small for gestational age
 Yes856 (2.6)52 (3.6)1.39 (1.05–1.85)1.28 (0.94–1.75)
 Missing72 (0.2)3 (0.2)
Mode of delivery
 Vaginal/instrumental25 809 (79.7)1046 (73.1)Ref.Ref.
 Elective caesarean section2807 (8.7)170 (11.2)1.49 (1.26–1.77)1.49 (1.24–1.78)
 Emergency caesarean section3387 (10.5)187 (13.1)1.36 (1.16–1.60)1.32 (1.11–1.57)
 Unknown caesarean section396 (1.2)27 (1.9)

Data are presented as n (%), unless otherwise stated. #: adjusted for maternal smoking, obesity, education, country of birth, parity and depression/anxiety, and infant sex; : approximately mean±1sd in population.