TABLE 1

Characteristics of included coronavirus disease 2019 (COVID-19) population

CharacteristicsAsthmaCOPDNo asthma or COPDp-value
Subjects n3544324318
Age median (IQR)47.5 (24.1)76.8 (13.7)53.0 (30.0)<0.001
Age groups<0.001
 <65 years291 (82.2)73 (16.9)3036 (70.3)
 65–74 years30 (8.5)118 (27.3)495 (11.5)
 ≥75 years33 (9.3)241 (55.8)787 (18.2)
Female sex217 (61.3)220 (50.9)2268 (52.5)
Household income<0.004
 Lowest quartile79 (22.3)154 (35.6)1043 (24.1)
 Second lowest quartile75 (21.2)176 (40.7)1025 (23.7)
 Second highest quartile95 (26.8)75 (17.4)1106 (25.6)
 Highest quartile105 (29.7)27 (6.2)1144 (26.5)
Highest completed education<0.001
 Upper or lower secondary school85 (24.0)188 (43.5)1096 (25.4)
 Vocational upper secondary school108 (30.5)182 (42.1)1616 (37.4)
 Medium-cycle higher education or bachelors' degree109 (30.8)49 (11.3)1100 (25.5)
 Long-cycle higher education52 (14.7)13 (3.0)506 (11.7)
Civil status
 Single116 (32.8)217 (50.2)1544 (35.8)<0.001
 Married or cohabiting238 (67.2)215 (49.8)2774 (64.2)
Origin
 Danish281 (79.4)392 (90.7)3518 (81.5)<0.001
 Immigrants or immigrants' descendants73 (20.6)40 (9.3)800 (18.5)
Comorbidities
 Ischaemic heart disease10 (2.8)98 (22.7)271 (6.3)<0.001
 Previous myocardial infarction9 (2.5)96 (22.2)232 (5.4)<0.001
 Heart failure7 (2.0)83 (19.2)147 (3.4)<0.001
 Atrial fibrillation or flutter27 (7.6)139 (32.2)474 (11.0)<0.001
 Cerebral vascular disease13 (3.7)91 (21.1)276 (6.4)<0.001
 Diabetes34 (9.6)109 (25.2)455 (10.5)<0.001
 Chronic kidney disease7 (2.0)63 (14.6)214 (5.0)<0.001
Blood eosinophil count# ×109 cells·L−1 mean±sd0.17±0.210.15±0.140.13±0.17<0.001
Treatment
 Short-acting β-agonists112 (31.6)169 (39.1)98 (2.3)<0.001
 Long-acting β-agonists130 (36.7)260 (60.2)23 (0.5)<0.001
 Long-acting muscarinergic antagonists17 (4.8)200 (46.3)10 (0.2)<0.001
 Inhaled corticosteroids178 (50.3)187 (43.3)40 (0.9)<0.001
 Leukotriene receptor antagonists42 (11.9)12 (2.8)0 (0)<0.001
 Antihistamines67 (18.9)47 (10.9)261 (6.0)<0.001
 Systemic corticosteroids41 (11.6)90 (20.8)156 (3.6)<0.001

Data are presented as n (%) unless otherwise stated. Total n=5104. IQR: interquartile range. #: out of the total population, 2923 patients with COVID-19 had blood eosinophil counts within the last 5 years. : frequency of different types of medication from the last 12 months were estimated; if a patient received combination therapy, for example inhaled corticosteroids and a long-acting β-agonist, the medications were split up into their generic forms; treatment with systemic corticosteroids was defined as any prescription filled within the last 12 months.