TABLE 2

Demographic, physiological and laboratory data according to treatment groups

only oxygen
(1) N=53
NHF/CPAP/NIV
(2) N=17
invasive MV
(3) N=8
Age65±1562±1373±9
BMI29.4±5.229.6±5.129.1±2.5
LOS (days)10.1±6.7(2,3)19.3±11.8(1,3)34±26.9(1,2)
temperature °C38.3±1(2)39.1±0.9 (1)39.1±0.5
SaO2 (%)93.1±3.7(3)91.6±6(3)85.4±10.6 (1,2)
respiratory rate /min20.6±4.4(2)25.7±6.7 (1)23.5±7.6
heart rate /min90±2099±1695±21
RR systolic (mmHg)118±21110±22103±23
RR diastolic (mmHg)69±1168±1063±13
Hemoglobin nadir (mg·dL−1)12.4±1.912.1±211±2.4
Leucocytes nadir /µL5745±27325724±26025512±1629
Lymphocytes nadir/µL986±2015553±262469±342
LDH max (U·L−1)405±129(2,3)562±260(1,3)741±190(1,2)
BNP max (pg·mL−1)1773±3086669±895(3)5258±7659(2)
CRP max (mg·dL−1)10.9±7.1(2,3)21.6±9.2(1)26.4±12.3(1)
PCT max (ng·mL−1)0.9±2(3)0.8±1.2(3)3±2.9(1,2)
Creatinine max (mg·dL−1)1.25±0.62(3)1±0.3(3)2.6±1.4(1,2)
D-Dimer max (ng·mL−1)1530±1575(3)2698±24646574±5321(1)
Troponin max (µg·L−1)28.5±39(3)25.9±33.1(3)467±1047(1,2)
PO2 nadir (mmHg)54.5±1147.8±10.545.9±6.8

LOS: length of (hospital) stay; SaO2: oxygen saturation; RR: blood pressure; LDH: lactate dehydrogenase; BNP: brain natriuretic peptide; CRP: C-reactive protein; PCT: procalcitonin; PO2: partial pressure of oxygen; nadir: lowest measured value; max: maximal measured value. Number in brackets indicate significant differences to the respective column (p<0.05).