TABLE 1

Clinical characteristics (n=224)

Age years67.0±11.9 (31–95)
Male/female n50/174
BMI kg·m−219.3±2.6 (13.2–26.8)
Smoker64 (28.6)
Smoking pack-years9±20 (0–135)
Previous history of pulmonary TB28 (12.5)
Comorbidities56 (25.0)
 Asthma19 (8.5)
 Diabetes mellitus15 (6.7)
 COPD9 (4.0)
 Rheumatoid arthritis7 (3.1)
 Chronic interstitial pneumonia4 (1.8)
 Chronic heart failure2 (0.9)
 Pneumoconiosis1 (0.4)
Use of immunosuppressants8 (3.6)
Symptoms170 (75.9)
 Cough141 (62.9)
 Sputum108 (48.2)
 Dyspnoea38 (17.0)
 Haemoptysis49 (21.9)
 Fever23 (10.3)
 Fatigue15 (6.7)
 Weight loss47 (21.0)
Positive sputum AFB smear74 (33.0)
Causative organisms
 Mycobacterium avium139 (62.1)
 Mycobacterium intracellulare101 (45.1)
 Co-infections#16 (7.1)
Radiological types
 Nodular bronchiectatic173 (77.2)
 Fibrocavitary48 (21.4)
 Unclassifiable3 (1.3)
MAC-PD score9.0±4.6 (2.0–26.0)
MAC-PD status
 Progressive disease103 (46.0)
 Stationary disease+121 (54.0)
PPFE score0.9±1.4 (0.0–7.0)
 Limited56 (25.0)
 Extensive32 (14.3)
Presence of PPFE59 (26.3)
Presence of apical cap29 (12.9)

Data are presented as mean±sd (range) or n (%), unless otherwise stated. BMI: body mass index; TB: tuberculosis; AFB: acid-fast bacilli; MAC-PD: M. avium complex pulmonary disease; PPFE: pleuroparenchymal fibroelastosis. #: co-infections of M. avium and M. intracellulare; : a case requiring multidrug treatment within 3 years of diagnosis due to clinical or radiological deterioration; +: a case stable for ≥3 years after diagnosis without clinical or radiological deterioration.