Overall cohort | Non-statin users | Statin users | p-value | |
Subjects n | 448 | 294 | 154 | |
Age years | 73.5 (60–84) | 68 (54–83) | 79 (71–85) | <0.001 |
Female sex | 234 (52.2) | 167 (56.8) | 67 (43.5) | 0.007 |
Hypertension | 247 (55.1) | 125 (42.5) | 122 (79.2) | <0.001 |
Diabetes mellitus | 97 (21.7) | 36 (12.2) | 61 (39.6) | <0.001 |
Current smoker | 73 (16.3) | 53 (18.0) | 20 (13.0) | 0.16 |
CAD | 46 (10.3) | 5 (1.7) | 41 (26.6) | <0.001 |
Heart failure | 53 (11.8) | 19 (6.5) | 34 (22.1) | <0.001 |
PAD | 35 (7.8) | 7 (2.4) | 28 (18.2) | <0.001 |
CVD | 24 (5.4) | 7 (2.4) | 17 (11.0) | <0.001 |
COPD | 81 (18.1) | 54 (18.4) | 27 (17.5) | 0.83 |
Cancer | 122 (27.2) | 83 (28.2) | 39 (25.3) | 0.51 |
Influenza vaccination | 185 (42.9) | 96 (33.9) | 89 (60.1) | <0.001 |
Haemoglobin g·dL−1 | 13.0 (11.8–14.0) | 13.0 (11.8–14.1) | 13.0 (11.7–14.0) | 0.43 |
Platelets ×103 cells·µL−1 | 204 (152–259) | 207 (155–267) | 195 (150–234) | 0.15 |
Leukocytes ×103 cells·µL−1 | 7.9 (5.5–10.6) | 7.7 (5.0–10.2) | 8.1 (6.0–11.6) | 0.81 |
Neutrophils ×103 cells·µL−1 | 6.0 (3.7–8.9) | 5.8 (3.3–8.6) | 6.6 (4.5–9.3) | 0.41 |
GFR mL·min−1 per 1.73 m2 | 80 (60–96) | 86 (68–101) | 72 (55–84) | <0.001 |
CRP peak mg·dL−1 | 5.8 (2.5–17.1) | 5.8 (2.4–16.9) | 6.0 (2.7–18.0) | 0.76 |
Data are presented as median (interquartile range) or n (%), unless otherwise stated. CAD: coronary artery disease; PAD: peripheral artery disease; CVD: cerebrovascular disease; GFR: glomerular filtration rate; CRP: C-reactive protein. p-value denotes comparison between statin and non-statin users. Bold indicates statistical significance.